about
Positively-charged, porous, polysaccharide nanoparticles loaded with anionic molecules behave as 'stealth' cationic nanocarriersDesign and antileishmanial activity of amphotericin B-loaded stable ionic amphiphile biovector formulations.Evolution of availability of curcumin inside poly-lactic-co-glycolic acid nanoparticles: impact on antioxidant and antinitrosant properties.Characterization of a benzyl-phenoxy-ethanamine binding protein in Trypanosoma equiperdum and the possible relation between binding affinity and trypanocidal activity.A new family of carriers (biovectors) enhances the immunogenicity of rabies antigens.Chapter 1 - Drug delivery to the brain using colloidal carriers.Drug delivery systems in the treatment of African trypanosomiasis infections.Airway delivery of peptides and proteins using nanoparticles.HBHA vaccination may require both Th1 and Th17 immune responses to protect mice against tuberculosis.Vectorization by nanoparticles decreases the overall toxicity of airborne pollutants.Synthetic parasites: a successful mucosal nanoparticle vaccine against Toxoplasma congenital infection in mice.Influence of the surface charge of PLGA nanoparticles on their in vitro genotoxicity, cytotoxicity, ROS production and endocytosis.Development and validation of a reversed-phase HPLC method for the quantification of paclitaxel in different PLGA nanocarriers.Porous nanoparticles as delivery system of complex antigens for an effective vaccine against acute and chronic Toxoplasma gondii infection.Development of innovative paclitaxel-loaded small PLGA nanoparticles: study of their antiproliferative activity and their molecular interactions on prostatic cancer cells.Transferrin adsorption onto PLGA nanoparticles governs their interaction with biological systems from blood circulation to brain cancer cells.Nasal nanovaccines.Study of serum interaction with a cationic nanoparticle: Implications for in vitro endocytosis, cytotoxicity and genotoxicity.Ex vivo stimulation and expansion of both CD4(+) and CD8(+) T cells from peripheral blood mononuclear cells of human cytomegalovirus-seropositive blood donors by using a soluble recombinant chimeric protein, IE1-pp65Characterization of endocytosis and exocytosis of cationic nanoparticles in airway epithelium cells.Mechanisms allowing protein delivery in nasal mucosa using NPL nanoparticles.Combination of human cytomegalovirus recombinant immediate-early protein (IE1) with 80 nm cationic biovectors: protection from proteolysis and potentiation of presentation to CD4+ T-cell clones in vitro.Development of a nanoparticulate formulation of diminazene to treat African trypanosomiasis.Development of transferrin functionalized poly(ethylene glycol)/poly(lactic acid) amphiphilic block copolymeric micelles as a potential delivery system targeting brain glioma.Head-to-head comparison of four nonadjuvanted inactivated cell culture-derived influenza vaccines: effect of composition, spatial organization and immunization route on the immunogenicity in a murine challenge model.Activation of invariant Natural Killer T lymphocytes in response to the α-galactosylceramide analogue KRN7000 encapsulated in PLGA-based nanoparticles and microparticles.Stabilization of human tyrosine hydroxylase in maltodextrin nanoparticles for delivery to neuronal cells and tissue.Characterization of endocytosis of transferrin-coated PLGA nanoparticles by the blood-brain barrier.Solubilization of α-galactosylceramide in aqueous medium: Impact on Natural Killer T cell activation and antitumor responses.Influence of surface charge and inner composition of porous nanoparticles to cross blood-brain barrier in vitro.Preparation and characterization of novel chitosan and β-cyclodextrin polymer sponges for wound dressing applications.Improvement of sublingual immunotherapy efficacy with a mucoadhesive allergen formulation.Efficacy of sublingual vectorized recombinant Bet v 1a in a mouse model of birch pollen allergic asthma.Effect of prior heavy exercise on muscle deoxygenation kinetics at the onset of subsequent heavy exercise.Effects of gamma- and hydroxypropyl-gamma-cyclodextrins on the transport of doxorubicin across an in vitro model of blood-brain barrier.Structural characterization of organized systems of polysaccharides and phospholipids by light scattering spectroscopy and electron microscopyPorous Nanoparticles With Self-Adjuvanting M2e-Fusion Protein and Recombinant Hemagglutinin Provide Strong and Broadly Protective Immunity Against Influenza Virus InfectionsResidence time and uptake of porous and cationic maltodextrin-based nanoparticles in the nasal mucosa: Comparison with anionic and cationic nanoparticlesInfluence of surface charge and inner composition of nanoparticles on intracellular delivery of proteins in airway epithelial cellsPreface
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հետազոտող
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Didier Betbeder
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Didier Betbeder
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Didier Betbeder
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Didier Betbeder
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