Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease

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Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease

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http://www.wikidata.org/entity/Q57044776

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im Oktober 2018 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2018

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name

Mitochondrial Stasis Reveals p ...... nalcoholic Fatty Liver Disease

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Mitochondrial Stasis Reveals p ...... nalcoholic Fatty Liver Disease

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Item

label

Mitochondrial Stasis Reveals p ...... nalcoholic Fatty Liver Disease

@en

Mitochondrial Stasis Reveals p ...... nalcoholic Fatty Liver Disease

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prefLabel

Mitochondrial Stasis Reveals p ...... nalcoholic Fatty Liver Disease

@en

Mitochondrial Stasis Reveals p ...... nalcoholic Fatty Liver Disease

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P1476

Mitochondrial Stasis Reveals p ...... nalcoholic Fatty Liver Disease

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P2093

Atsushi Igarashi

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Daisuke Murata

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Hiromi Sesaki

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Kie Itoh

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Miho Iijima

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Richard L Huganir

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Shoichiro Kameoka

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Takashi Kato

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Tatsuya Yamada

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Toru Yanagawa

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P2860

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

A Mechanistic Review of Mitophagy and Its Role in Protection against Alcoholic Liver Disease

Recent advances into the understanding of mitochondrial fission

P304

588-604.e5

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scholarly article

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10.1016/J.CMET.2018.06.014

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Ted M. Dawson

Koji Okamoto

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2018-10-02T00:00:00Z

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P698

30017357

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P921

protein ubiquitination

mitochondrion

cell biology

molecular biology

P932

6170673

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