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Hemopressin Peptides as Modulators of the Endocannabinoid System and their Potential Applications as Therapeutic Tools.Synthesis and evaluation of new endomorphin-2 analogues containing (Z)-alpha,beta-didehydrophenylalanine (Delta(Z)Phe) residues.2,5-diketopiperazines as neuroprotective agents.Synthesis and pharmacological screening of a large library of 1,3,4-thiadiazolines as innovative therapeutic tools for the treatment of prostate cancer and melanoma.A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms.Identification of new anti-Candida compounds by ligand-based pharmacophore virtual screening.Signal transduction pathways triggered by selective formylpeptide analogues in human neutrophils.Synthesis and evaluation of new endomorphin analogues modified at the Pro(2) residue.Traditionally Used Lathyrus Species: Phytochemical Composition, Antioxidant Activity, Enzyme Inhibitory Properties, Cytotoxic Effects, and in silico Studies of L. czeczottianus and L. nissoliaProdrug approach for increasing cellular glutathione levels.Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control.Synthesis and bioactivity of secondary metabolites from marine sponges containing dibrominated indolic systems.Cyclotides: a natural combinatorial peptide library or a bioactive sequence player?DPP-4 inhibitors: a patent review (2012 - 2014).Nitric oxide donors and selective carbonic anhydrase inhibitors: a dual pharmacological approach for the treatment of glaucoma, cancer and osteoporosis.Twisted nanoribbons from a RGD-bearing cholic acid derivative.The design of multitarget ligands for chronic and neuropathic pain.Fluorescent-labeled bioconjugates of the opioid peptides biphalin and DPDPE incorporating fluorescein-maleimide linkers.Synthesis and anti-cancer activity of naturally occurring 2,5-diketopiperazines.The Positive Regulation of eNOS Signaling by PPAR Agonists in Cardiovascular Diseases.Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms.Microwave-assisted extraction, HPLC analysis, and inhibitory effects on carbonic anhydrase I, II, VA, and VII isoforms of 14 blueberry Italian cultivars.Study of synthetic peptides derived from the PKI55 protein, a protein kinase C modulator, in human neutrophils stimulated by the methyl ester derivative of the hydrophobic N-formyl tripeptide for-Met-Leu-Phe-OH.Synthesis, Characterization, and DNA Binding Profile of a Macrocyclic β-Sheet Analogue of ARC Protein.Nitrobenzoxadiazole-based GSTP1-1 inhibitors containing the full peptidyl moiety of (pseudo)glutathione.Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties.Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents.A Multidirectional Perspective for Novel Functional Products: In vitro Pharmacological Activities and In silico Studies on Ononis natrix subsp. hispanicaNovel cyclic biphalin analogue with improved antinociceptive properties.Cytotoxic and Enzyme Inhibitory Potential of Two Potentilla species (P. speciosa L. and P. reptans Willd.) and Their Chemical Composition.Analgesic Properties of Opioid/NK1 Multitarget Ligands with Distinct in Vitro Profiles in Naive and Chronic Constriction Injury Mice.Isopeptide bonds in chemotactic tripeptides. Synthesis and activity of lysine-containing fMLF analogs.Antinociceptive profile of potent opioid peptide AM94, a fluorinated analogue of biphalin with non-hydrazine linker.Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors.Potent biphalin analogs with µ/δ mixed opioid activity: in vivo and in vitro biological evaluation.Opioid Receptor Activity and Analgesic Potency of DPDPE Peptide Analogues Containing a Xylene Bridge.Design, Synthesis and Biological Evaluation of Two Opioid Agonist and Cav 2.2 Blocker Multitarget Ligands.Hybrid peptides endomorphin-2/DAMGO: design, synthesis and biological evaluation.Hybrid alpha/beta3-peptides with proteinogenic side chains. Monosubstituted analogues of the chemotactic tripeptide For-Met-Leu-Phe-OMe.Peptides containing 4-amino-1,2-dithiolane-4-carboxylic acid (Adt): conformation of Boc-Adt-Adt-NHMe and NH...S interactions.
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Adriano Mollica
@ast
Adriano Mollica
@en
Adriano Mollica
@es
Adriano Mollica
@nl
type
label
Adriano Mollica
@ast
Adriano Mollica
@en
Adriano Mollica
@es
Adriano Mollica
@nl
prefLabel
Adriano Mollica
@ast
Adriano Mollica
@en
Adriano Mollica
@es
Adriano Mollica
@nl
P106
P1153
7003364903
P21
P31
P496
0000-0002-7242-4860