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Enhancement of radiosensitivity by the novel anticancer quinolone derivative vosaroxin in preclinical glioblastoma models.KPT-330, a potent and selective exportin-1 (XPO-1) inhibitor, shows antitumor effects modulating the expression of cyclin D1 and survivin [corrected] in prostate cancer models.The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma.Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model.The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models.Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer.Dual PI3K/mTOR inhibitor, XL765 (SAR245409), shows superior effects to sole PI3K [XL147 (SAR245408)] or mTOR [rapamycin] inhibition in prostate cancer cell models.XPO1/CRM1-selective inhibitors of nuclear export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa).Trifluoroibuprofen inhibits α-methylacyl coenzyme A racemase (AMACR/P504S), reduces cancer cell proliferation and inhibits in vivo tumor growth in aggressive prostate cancer models.Crocus sativus stigma extract and its major constituent crocin possess significant antiproliferative properties against human prostate cancer.PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and CRM1 in preclinical models of prostate cancer.Increased levels of DNA methyltransferases are associated with the tumorigenic capacity of prostate cancer cells.Antitumor effects of saffron-derived carotenoids in prostate cancer cell models.ATPS-72A NOVEL CXCR4 ANTAGONIST COMBINES SYNERGISTICALLY WITH BEVACIZUMAB AND SUNITINIB TO INHIBIT PROGRESSION OF GLIOBLASTOMA.Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer.Effects of Crocetin Esters and Crocetin from Crocus sativus L. on Aortic Contractility in Rat Genetic Hypertension.The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma.Dual PI3 K/mTOR inhibition reduces prostate cancer bone engraftment altering tumor-induced bone remodeling.Correction to: The first-in-class alkylating deacetylase inhibitor molecule tinostamustine shows antitumor effects and is synergistic with radiotherapy in preclinical models of glioblastoma.CXCR4 pharmacogical inhibition reduces bone and soft tissue metastatic burden by affecting tumor growth and tumorigenic potential in prostate cancer preclinical models.Crocetin, a Carotenoid Derived from Saffron (Crocus sativus L.), Improves Acetylcholine-Induced Vascular Relaxation in Hypertension
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Andrea Mancini
@ast
Andrea Mancini
@en
Andrea Mancini
@es
Andrea Mancini
@nl
type
label
Andrea Mancini
@ast
Andrea Mancini
@en
Andrea Mancini
@es
Andrea Mancini
@nl
prefLabel
Andrea Mancini
@ast
Andrea Mancini
@en
Andrea Mancini
@es
Andrea Mancini
@nl
P106
P31
P496
0000-0002-5215-9297