about
Structural basis for distinct functions of the naturally occurring Cys mutants of human apolipoprotein A-IAmyloidogenic mutations in human apolipoprotein A-I are not necessarily destabilizing - a common mechanism of apolipoprotein A-I misfolding in familial amyloidosis and atherosclerosisStructure and selectivity of a monovalent cation binding site in cubic insulin crystals.Pressure perturbation calorimetry of apolipoproteins in solution and in model lipoproteinsEffects of cholesterol on thermal stability of discoidal high density lipoproteins.Effects of protein oxidation on the structure and stability of model discoidal high-density lipoproteinsAggregation and fusion of low-density lipoproteins in vivo and in vitro.Thermodynamic stability of a kappaI immunoglobulin light chain: relevance to multiple myeloma.Effects of phospholipase A(2) and its products on structural stability of human LDL: relevance to formation of LDL-derived lipid droplets.Thermal transitions in serum amyloid A in solution and on the lipid: implications for structure and stability of acute-phase HDL.Structural stability and functional remodeling of high-density lipoproteins.Apolipoprotein structure and dynamics.Crystal structure of Δ(185-243)ApoA-I suggests a mechanistic framework for the protein adaptation to the changing lipid load in good cholesterol: from flatland to sphereland via double belt, belt buckle, double hairpin and trefoil/tetrafoilStructural Stability and Local Dynamics in Disease-Causing Mutants of Human Apolipoprotein A-I: What Makes the Protein Amyloidogenic?Structure of serum amyloid A suggests a mechanism for selective lipoprotein binding and functions: SAA as a hub in macromolecular interaction networks.Effects of acyl chain length, unsaturation, and pH on thermal stability of model discoidal HDLs.Role of secondary structure in protein-phospholipid surface interactions: reconstitution and denaturation of apolipoprotein C-I:DMPC complexesDifferential stability of high-density lipoprotein subclasses: effects of particle size and protein composition.Folded functional lipid-poor apolipoprotein A-I obtained by heating of high-density lipoproteins: relevance to high-density lipoprotein biogenesis.Hot spots in apolipoprotein A-II misfolding and amyloidosis in mice and men.Role of apolipoprotein A-II in the structure and remodeling of human high-density lipoprotein (HDL): protein conformational ensemble on HDL.Amyloid-Forming Properties of Human Apolipoproteins: Sequence Analyses and Structural InsightsThermal stability of human plasma electronegative low-density lipoprotein: A paradoxical behavior of low-density lipoprotein aggregation.Pressure perturbation calorimetry of lipoproteins reveals an endothermic transition without detectable volume changes. Implications for adsorption of apolipoprotein to a phospholipid surface.High- and low-temperature unfolding of human high-density apolipoprotein A-2.Monitoring protein aggregation during thermal unfolding in circular dichroism experiments.Human plasma high-density lipoproteins are stabilized by kinetic factors.Poly(ethylene glycol)-induced fusion and destabilization of human plasma high-density lipoproteins.Structural basis for thermal stability of human low-density lipoprotein.Electrostatic effects on the stability of discoidal high-density lipoproteins.Hereditary Renal Amyloidosis Associated With a Novel Apolipoprotein A-II Variant.Serum amyloid A self-assembles with phospholipids to form stable protein-rich nanoparticles with a distinct structure: A hypothetical function of SAA as a "molecular mop" in immune response.Structural and Immunological Characterization of Novel Recombinant MOMP-Based Chlamydial Antigens.Serum amyloid A forms stable oligomers that disrupt vesicles at lysosomal pH and contribute to the pathogenesis of reactive amyloidosis.Paradoxical effects of SAA on lipoprotein oxidation suggest a new antioxidant function for SAA.Triglyceride increase in the core of high-density lipoproteins augments apolipoprotein dissociation from the surface: Potential implications for treatment of apolipoprotein deposition diseases.Structure of serum amyloid A suggests a mechanism for selective lipoprotein binding and functions: SAA as a hub in macromolecular interaction networks.In vitro co-expression of human amyloidogenic immunoglobulin light and heavy chain proteins: a relevant cell-based model of AL amyloidosis.Structural stability and local dynamics in disease-causing mutants of human apolipoprotein a-I: what makes the protein amyloidogenic?Molecular Insights into Human Hereditary Apolipoprotein A-I Amyloidosis Caused by the Glu34Lys Mutation
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Olga Gursky
@ast
Olga Gursky
@en
Olga Gursky
@es
Olga Gursky
@nl
type
label
Olga Gursky
@ast
Olga Gursky
@en
Olga Gursky
@es
Olga Gursky
@nl
prefLabel
Olga Gursky
@ast
Olga Gursky
@en
Olga Gursky
@es
Olga Gursky
@nl
P106
P31
P496
0000-0002-8598-4824