Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis

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Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis

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wetenschappelijk artikel

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наукова стаття, опублікована у вересні 2018

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Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis

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Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis

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Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis

@en

Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis

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Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis

@en

Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis

@nl

P1476

Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis

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P2093

Albert Stanek

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Antonio E Alfonso

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Cathy Mueller

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Chongmin Huan

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Devon John

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Kaylene Barrera

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Kei Okochi

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Peiqi Ou

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Scott Tenner

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Zuzanna Niewiadomska

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P2860

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene

Protective effect against Parkinson's disease-related insults through the activation of XBP1

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

The ER stress factor XBP1s prevents amyloid-beta neurotoxicity

Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: a novel disease mechanism

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

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37-46

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scholarly article

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10.4291/WJGP.V9.I2.37

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English

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P478

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P577

2018-09-29T00:00:00Z

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30283709

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6163129

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