about
Protease nexin-1 interacts with thrombomodulin and modulates its anticoagulant effectAnticoagulant and antithrombotic properties of platelet protease nexin-1Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamilyRoles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activationProtease nexin-1: a cellular serpin down-regulated by thrombin in rat aortic smooth muscle cellsSwitch from protective to adverse inflammation during influenza: viral determinants and hemostasis are caught as culprits.Anti GPVI human antibodies neutralizing collagen-induced platelet aggregation isolated from a combinatorial phage display library.Thrombin receptor induction by injury-related factors in human skeletal muscle cells.Modulation of protease nexin-1 activity by polysaccharides.Exploring the platelet proteome via combinatorial, hexapeptide ligand libraries.Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment.Heterogeneity of platelet functional alterations in patients with filamin A mutations.Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex-mediated inflammation in mice.Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks.Design and humanization of a murine scFv that blocks human platelet glycoprotein VI in vitro.Collagen can selectively trigger a platelet secretory phenotype via glycoprotein VI.A humanized glycoprotein VI (GPVI) mouse model to assess the antithrombotic efficacies of anti-GPVI agents.Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators.Inhibition of Glycoprotein VI Clustering by Collagen as a Mechanism of Inhibiting Collagen-Induced Platelet Responses: The Example of Losartan.Non-invasive molecular imaging of fibrosis using a collagen-targeted peptidomimetic of the platelet collagen receptor glycoprotein VIDistinct spatio-temporal Ca2+ signaling elicited by integrin alpha2beta1 and glycoprotein VI under flow.Emerging role of serpinE2/protease nexin-1 in hemostasis and vascular biology.The future of glycoprotein VI as an antithrombotic target.New advances in treating thrombotic diseases: GPVI as a platelet drug target.Affinity of low molecular weight fucoidan for P-selectin triggers its binding to activated human platelets.Bioreactivity of stent material: Activation of platelets, coagulation, leukocytes and endothelial cell dysfunction in vitro.Alteplase Reduces Downstream Microvascular Thrombosis and Improves the Benefit of Large Artery Recanalization in Stroke.Abacavir has no prothrombotic effect on platelets in vitro.Platelet activation and aggregation promote lung inflammation and influenza virus pathogenesis.In vitro and in vivo antiangiogenic properties of the serpin protease nexin-1Thrombin interaction with a recombinant N-terminal extracellular domain of the thrombin receptor in an acellular system.Hemostatic disorders in a JAK2V617F-driven mouse model of myeloproliferative neoplasmIdentification of residues within human glycoprotein VI involved in the binding to collagen: evidence for the existence of distinct binding sites.Activation state of platelets in experimental severe hemophilia A.Expression and function of the collagen receptor GPVI during megakaryocyte maturation.Increased expression of protease nexin-1 in fibroblasts during idiopathic pulmonary fibrosis regulates thrombin activity and fibronectin expression.Thrombin downregulates muscle acetylcholine receptors via an IP3 signaling pathway by activating its G-protein-coupled protease-activated receptor-1.Glycoprotein Ib-mediated platelet activation. A signalling pathway triggered by thrombin.Atorvastatin limits the pro-inflammatory response of rat aortic smooth muscle cells to thrombin.Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation.
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Martine Jandrot-Perrus
@ast
Martine Jandrot-Perrus
@en
Martine Jandrot-Perrus
@es
Martine Jandrot-Perrus
@nl
type
label
Martine Jandrot-Perrus
@ast
Martine Jandrot-Perrus
@en
Martine Jandrot-Perrus
@es
Martine Jandrot-Perrus
@nl
prefLabel
Martine Jandrot-Perrus
@ast
Martine Jandrot-Perrus
@en
Martine Jandrot-Perrus
@es
Martine Jandrot-Perrus
@nl
P106
P31
P496
0000-0002-8450-9247