Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation - Wikidata - wikimedia - TriplyDB

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

http://www.wikidata.org/entity/Q57109903

about

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

http://www.wikidata.org/entity/Q57109903

description

im September 2018 veröffentlichter wissenschaftlicher Artikel

@de

scientific article published on 05 July 2018

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована у вересні 2018

@uk

name

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

@en

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

@nl

type

label

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

@en

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

@nl

prefLabel

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

@en

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

@nl

P1433

Q57109903-124BA270-E1E2-4A72-96A3-C13D43E8543A

P1476

Q57109903-C02CECAF-1572-4957-AE74-907DFF8DC511

P2093

Q57109903-4DB5C79B-B427-4E0A-A97D-AE92FF986997

Q57109903-9C5EE5DE-3D68-4776-A3B9-2CD315D7A274

Q57109903-BB6F73BA-B916-467E-BF05-4E2EB6423AEB

Q57109903-E3ECAF7A-771D-49BD-931F-BA6274B6AF72

Q57109903-EEAB9CC3-8523-40A8-9C02-E11D68E1EFAF

Q57109903-F3354FCA-793D-42DC-88FD-F4394DCE123C

P2860

Q57109903-0B24B643-8323-4803-BC8E-7B742FB60F4C

Q57109903-23FBFA2D-2CD3-4B2A-BFEF-8B5713802E13

Q57109903-2479DB79-7266-4FC9-9489-F7E37D38CC78

Q57109903-34071C58-34FB-4A40-8E37-70C788CAD5A0

Q57109903-3B73F5F0-1847-402C-946D-80BDB0AFDCC1

Q57109903-4DD7E82B-A085-46CD-B793-A40FC6E49EB2

Q57109903-50831A31-BCCD-40BF-BEC8-C2B92CCEEC06

Q57109903-73F11311-4B88-429E-B519-5EA952241FC2

Q57109903-7FA5FC94-9AD4-48F4-8174-26D2696028EE

Q57109903-8115A737-00E3-4D0B-B395-45AB7054A265

P304

Q57109903-BF23A715-6B47-48D6-A425-26D17195CB78

P31

Q57109903-4312992F-1E03-4687-B73B-000721875FA3

P356

Q57109903-C25DA033-31F5-4F5E-A5D0-805B6B760A97

P407

Q57109903-8C8A96DB-083C-498A-B279-DD22A6A646F5

P433

Q57109903-A17AF441-7F9E-40A4-8B91-1C97ABFEE86A

P478

Q57109903-798946FE-1810-4893-88D4-7FCCC681C58A

P50

Q57109903-7BD0D302-F7E2-4056-B695-B0C8634D6293

P577

Q57109903-01F54B95-E21F-4467-9B25-3B8A05638A5D

P698

Q57109903-C6E838AE-B722-4532-B0D5-3B2FFF8B8057

P921

Q57109903-A5C4D037-BF02-40F5-9A90-12989C51C7D6

Q57109903-C2740118-026C-4CD7-860D-EF7B9C8DD18D

Q57109903-D0887EC3-2177-469B-91DD-2A5909943D55

P932

Q57109903-FD79A888-7F0F-404B-9B73-20B5D929C71B

P356

P1433

Journal of Lipid Research

P1476

Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation

@en

P2093

Audrey L Keenan

http://www.w3.org/2001/XMLSchema#string

Makoto Miyazaki

http://www.w3.org/2001/XMLSchema#string

Moshe Levi

http://www.w3.org/2001/XMLSchema#string

Shinobu Miyazaki-Anzai

http://www.w3.org/2001/XMLSchema#string

Shohei Kohno

http://www.w3.org/2001/XMLSchema#string

Yuji Shiozaki

http://www.w3.org/2001/XMLSchema#string

P2860

Vitamin D receptor as an intestinal bile acid sensor

A G protein-coupled receptor responsive to bile acids

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

Quantitative real-time PCR protocol for analysis of nuclear receptor signaling pathways.

TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading.

Dual activation of the bile acid nuclear receptor FXR and G-protein-coupled receptor TGR5 protects mice against atherosclerosis.

Functional characterization of the semisynthetic bile acid derivative INT-767, a dual farnesoid X receptor and TGR5 agonist.

Effects of FXR in foam-cell formation and atherosclerosis development.

Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease.

Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output

P304

1709-1713

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1194/JLR.M087239

http://www.w3.org/2001/XMLSchema#string

P407

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

59

http://www.w3.org/2001/XMLSchema#string

P50

P577

2018-07-05T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29976576

http://www.w3.org/2001/XMLSchema#string

P921

atherosclerosis

P932

6121929

http://www.w3.org/2001/XMLSchema#string