about
Thyroid-hormone-disrupting chemicals: evidence for dose-dependent additivity or synergismThe next generation of risk assessment multiyear study - highlights of findings, applications to risk assessment, and future directionsShort-term exposure to triclosan decreases thyroxine in vivo via upregulation of hepatic catabolism in Young Long-Evans ratsCoordinated changes in xenobiotic metabolizing enzyme gene expression in aging male rats.Correlation of tissue concentrations of the pyrethroid bifenthrin with neurotoxicity in the rat.Evidence for dose-additive effects of pyrethroids on motor activity in ratsIncorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework.An assessment of dioxin exposure across gestation and lactation using a PBPK model and new data from Seveso.Dose-response relationships for induction of CYP1A1 and CYP1A2 enzyme activity in liver, lung, and skin in female mice following subchronic exposure to polychlorinated biphenyls.Screening methods for thyroid hormone disruptors.Relative potency for altered humoral immunity induced by polybrominated and polychlorinated dioxins/furans in female B6C3F1/N mice.Developmental triclosan exposure decreases maternal and neonatal thyroxine in rats.Employing a Mechanistic Model for the MAPK Pathway to Examine the Impact of Cellular all or None Behavior on Overall Tissue Response.A pharmacokinetic model of cis- and trans-permethrin disposition in rats and humans with aggregate exposure application.Mixtures research at NIEHS: an evolving program.Use of a physiologically based pharmacokinetic model for rats to study the influence of body fat mass and induction of CYP1A2 on the pharmacokinetics of TCDD.Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: a dynamic and kinetic evaluation of a putative mode-of-actionDevelopment of a refined database of mammalian relative potency estimates for dioxin-like compounds.Genomic Profiling Reveals Unique Molecular Alterations in Hepatoblastomas and Adjacent Hepatocellular Carcinomas in B6C3F1 Mice.Polybrominated dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds.An Intuitive Approach for Predicting Potential Human Health Risk with the Tox21 10k Library.Environmentally relevant pyrethroid mixtures: A study on the correlation of blood and brain concentrations of a mixture of pyrethroid insecticides to motor activity in the rat.Development of a quantitative model of pregnane X receptor (PXR) mediated xenobiotic metabolizing enzyme induction.Dioxins: model chemicals for assessing receptor-mediated toxicity.Tissue time course and bioavailability of the pyrethroid insecticide bifenthrin in the Long-Evans rat.In vitro metabolism of thyroxine by rat and human hepatocytes.F344/NTac Rats Chronically Exposed to Bromodichloroacetic Acid Develop Mammary Adenocarcinomas With Mixed Luminal/Basal Phenotype and Tgfβ Dysregulation.From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening.Short-term in vivo exposure to the water contaminant triclosan: Evidence for disruption of thyroxine.Physiologically based pharmacokinetic modeling of deltamethrin: development of a rat and human diffusion-limited model.Development of a quantitative model incorporating key events in a hepatotoxic mode of action to predict tumor incidence.In vivo acute exposure to polychlorinated biphenyls: effects on free and total thyroxine in rats.Subchronic Exposure of [3H]- 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in female B6C3F1 mice: relationship of steady-state levels to disposition and metabolism.Lack of antiandrogenic effects in adult male rats following acute exposure to 2,2-bis(4-chlorophenyl)-1,1-dichloroethylene (p,p'-DDE).Comparative responsiveness of hypothyroxinemia and hepatic enzyme induction in Long-Evans rats versus C57BL/6J mice exposed to TCDD-like and phenobarbital-like polychlorinated biphenyl congeners.EGF and TGF-alpha expression influence the developmental toxicity of TCDD: dose response and AhR phenotype in EGF, TGF-alpha, and EGF + TGF-alpha knockout mice.Physiologically based pharmacokinetic model for developmental exposures to TCDD in the rat.Dose-response assessment of the dermal toxicity of Virginia cedarwood oil in F344/N rats and B6C3F1/N mice.Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener.Environmentally relevant mixtures in cumulative assessments: an acute study of toxicokinetics and effects on motor activity in rats exposed to a mixture of pyrethroids.
P50
Q24810853-944D47AC-3B01-4310-85AF-F2EAB4CF608BQ26357739-F7AEB452-3B92-4690-8DEE-6F9A2ED406C7Q28396967-25149A42-1155-42F5-BA01-2003DDC4ADDCQ29347030-98AC17A7-F3ED-4828-BBC7-72BA08A099F3Q30395896-3FE29966-C66B-472F-8497-3E51EC3E9ED9Q30484589-C533A08E-0049-46D8-82ED-A4E5A7CF244BQ30662351-BD9135DA-5620-4A65-BA7E-0F08DB92D8F3Q31068651-86618E16-8E71-4788-8731-81C3CF6987A1Q31440189-2F6AD655-74F1-4981-950C-6FA9F2EDAF3EQ33598289-FBEFEA2F-2F68-4EC7-98DF-68234BC5B368Q33652479-7DFB73FB-2BB6-4967-862E-6D00FB4AE4BBQ34024337-2CA91F84-E7BC-4A65-BCA0-8494CA8DEFECQ34128970-A944213D-392F-4288-AF6F-D207D307A41EQ34292023-76071736-21A2-4A27-A925-AE5B45703AD4Q34512381-F8F507C1-11B4-45B7-83B8-42BC6AFC6DC0Q35039205-17E0581D-4E9C-42DE-A997-91F8ECA0C376Q36104027-DC4F484B-7851-43AB-B497-6A7F6C95F961Q36240045-7DE04987-908B-4B7E-9D6E-5CB3D39C08D0Q36348318-8C6CE4E3-85AE-40CF-AF57-48403CBA9C91Q36873760-C4D1B6E4-48DF-43C8-ADA3-2F746C7E12C1Q38624509-E38A49A3-55D2-4503-930E-0F0AC08EC3CEQ39665481-0040C236-335B-4B57-BDE7-4A1DC3C96931Q39901266-ED64195B-28E4-44A7-8904-57846F84BE7FQ40372009-55F7CDC0-67C3-44E1-B909-0FB8879CF0FDQ40542400-51ABAF6C-B882-47DE-AB58-8A8CE79AE897Q42447513-3557AAE4-7927-453F-BC19-B912AE3C73C0Q42473573-56E5992A-3C96-455B-9DA5-D26A6A794730Q42511311-ED13998D-A456-49B1-A8C9-9CEB6206B4BBQ42729540-19425B5C-E69B-4C32-ACF8-1B5C1BC70034Q43143778-F1AF770B-2A38-4A00-83A9-222B84A3C574Q43182582-1A9F5B42-9D6F-4BBB-86FF-9A0C7548539DQ43264852-F7CEB439-E7BB-4654-9239-E48859E3038FQ43607931-AFA9BB27-AC42-4603-8741-7C4440CA8176Q43977465-FC74BB8F-33E0-48B3-B351-BC65266C25E6Q44085259-4C81C818-D9E5-47BC-86FC-610877B6BBF3Q44273378-543BCC51-5106-4AC5-8BA7-23F4153906DAQ44824416-F195961D-E206-4719-973A-D801CAA8B93BQ45129177-40F45CF2-3D08-4D1D-9667-B2F56276EEB7Q46928347-2A157E00-8F73-43B8-B6B5-081015F92B89Q47292521-7070E048-3E1E-466A-B478-D70EEEAC1CCF
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Michael J DeVito
@ast
Michael J DeVito
@en
Michael J DeVito
@es
Michael J DeVito
@nl
type
label
Michael J DeVito
@ast
Michael J DeVito
@en
Michael J DeVito
@es
Michael J DeVito
@nl
prefLabel
Michael J DeVito
@ast
Michael J DeVito
@en
Michael J DeVito
@es
Michael J DeVito
@nl
P106
P1153
7003417616
P31
P496
0000-0003-1258-4894