about
Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits.Optimized pipeline of MuTect and GATK tools to improve the detection of somatic single nucleotide polymorphisms in whole-exome sequencing dataRevealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients.Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity.The role of toll-like receptors in chronic B-cell malignancies.Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: a new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients.Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression.HS1 has a central role in the trafficking and homing of leukemic B cells.A novel Rag2-/-gammac-/--xenograft model of human CLL.SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells.5'UTR point substitutions and N-terminal truncating mutations of ANKRD26 in acute myeloid leukemia.Fanconi anemia gene variants in therapy-related myeloid neoplasms.Mouse models in the study of chronic lymphocytic leukemia pathogenesis and therapy.The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia.Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models.Aneuploidy: Cancer strength or vulnerability?Network integration of multi-tumour omics data suggests novel targeting strategiesSynergism Through WEE1 and CHK1 Inhibition in Acute Lymphoblastic LeukemiaIdentification of Two DNMT3A Mutations Compromising Protein Stability and Methylation Capacity in Acute Myeloid LeukemiaChronic myeloid leukemia stem cells
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Giorgia Simonetti
@ast
Giorgia Simonetti
@en
Giorgia Simonetti
@es
Giorgia Simonetti
@nl
type
label
Giorgia Simonetti
@ast
Giorgia Simonetti
@en
Giorgia Simonetti
@es
Giorgia Simonetti
@nl
prefLabel
Giorgia Simonetti
@ast
Giorgia Simonetti
@en
Giorgia Simonetti
@es
Giorgia Simonetti
@nl
P106
P31
P496
0000-0001-6954-969X