Loss of angiotensin-converting enzyme 2 enhances TGF-β/Smad-mediated renal fibrosis and NF-κB-driven renal inflammation in a mouse model of obstructive nephropathy
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Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis protects against lung fibrosis by inhibiting the MAPK/NF-κB pathwayACE2: angiotensin II/angiotensin-(1-7) balance in cardiac and renal injuryLoss of ACE2 exacerbates murine renal ischemia-reperfusion injury.Chronic ANG II infusion induces sex-specific increases in renal T cells in Sprague-Dawley ratsRole of non-classical renin-angiotensin system axis in renal fibrosis.Therapeutic Effects of Tangshen Formula on Diabetic Nephropathy in Rats.Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling.Activation of angiotensin II type 2 receptor suppresses TNF-α-induced ICAM-1 via NF-кB: possible role of ACE2Angiotensin-(1-7): A Novel Peptide to Treat Hypertension and Nephropathy in Diabetes?ACE2, angiotensin-(1-7) and Mas receptor axis in inflammation and fibrosis.Tubular Overexpression of Angiopoietin-1 Attenuates Renal FibrosisACE2 alterations in kidney disease.Angiotensin-(1-7) relieved renal injury induced by chronic intermittent hypoxia in rats by reducing inflammation, oxidative stress and fibrosis.To RAS or not to RAS? The evidence for and cautions with renin-angiotensin system inhibition in patients with diabetic kidney disease.Non-canonical signalling and roles of the vasoactive peptides angiotensins and kinins.Metformin Prevents Renal Fibrosis in Mice with Unilateral Ureteral Obstruction and Inhibits Ang II-Induced ECM Production in Renal Fibroblasts.Downregulation of HIF1-α, Smad-2, AKT, and Bax gene expression in sodium nitrite-induced lung injury via some antioxidants.Immunologic Effects of the Renin-Angiotensin System.Sex differences in blood pressure control: are T lymphocytes the missing link?Plasticity of renal erythropoietin-producing cells governs fibrosis.Bcl-3 is a novel biomarker of renal fibrosis in chronic kidney disease.Modulation of leucocytic angiotensin-converting enzymes expression in patients maintained on high-permeable haemodialysis.SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction.Tumor necrosis factor α-converting enzyme inhibitor attenuates lipopolysaccharide-induced reactive oxygen species and mitogen-activated protein kinase expression in human renal proximal tubule epithelial cells.
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P2860
Loss of angiotensin-converting enzyme 2 enhances TGF-β/Smad-mediated renal fibrosis and NF-κB-driven renal inflammation in a mouse model of obstructive nephropathy
description
article
@en
im Februar 2012 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в лютому 2012
@uk
name
Loss of angiotensin-converting ...... del of obstructive nephropathy
@en
Loss of angiotensin-converting ...... del of obstructive nephropathy
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type
label
Loss of angiotensin-converting ...... del of obstructive nephropathy
@en
Loss of angiotensin-converting ...... del of obstructive nephropathy
@nl
prefLabel
Loss of angiotensin-converting ...... del of obstructive nephropathy
@en
Loss of angiotensin-converting ...... del of obstructive nephropathy
@nl
P2860
P50
P356
P1476
Loss of angiotensin-converting ...... del of obstructive nephropathy
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P2093
Xiao Ru Huang
P2860
P2888
P304
P356
10.1038/LABINVEST.2012.2
P577
2012-02-13T00:00:00Z
P6179
1028195183