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The Complex Role of STAT3 in Viral InfectionsHes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signallingNovel interactions between NFATc1 (Nuclear Factor of Activated T cells c1) and STAT-3 (Signal Transducer and Activator of Transcription-3) mediate G protein-coupled receptor agonist, thrombin-induced biphasic expression of cyclin D1, with first phasReal time analysis of STAT3 nucleocytoplasmic shuttling.Activation of T-cell protein-tyrosine phosphatase suppresses keratinocyte survival and proliferation following UVB irradiation.Intertissue flow of glutathione (GSH) as a tumor growth-promoting mechanism: interleukin 6 induces GSH release from hepatocytes in metastatic B16 melanoma-bearing mice.Essential role of CR6-interacting factor 1 (Crif1) in E74-like factor 3 (ELF3)-mediated intestinal developmentInterleukin-6 protects human macrophages from cellular cholesterol accumulation and attenuates the proinflammatory responseNF-κB and STAT3 - key players in liver inflammation and cancerCUEDC2 (CUE domain-containing 2) and SOCS3 (suppressors of cytokine signaling 3) cooperate to negatively regulate Janus kinase 1/signal transducers and activators of transcription 3 signaling.Tyrosine 705 Phosphorylation of STAT3 Is Associated with Phenotype Severity in TGFβ1 Transgenic Mice.Stat3 regulates microtubules by antagonizing the depolymerization activity of stathminAxonal regeneration in adult CNS neurons--signaling molecules and pathways.Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling.Crosstalk between signaling pathways of adrenoreceptors and signal transducers and activators of transcription 3 (STAT3) in heart.Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells.Both STAT3 activation and cholesterol efflux contribute to the anti-inflammatory effect of apoA-I/ABCA1 interaction in macrophages.Annexin A2 Coordinates STAT3 to Regulate the Invasion and Migration of Colorectal Cancer Cells In VitroPolymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant responseSignal transducer and activator of transcription-3 licenses Toll-like receptor 4-dependent interleukin (IL)-6 and IL-8 production via IL-6 receptor-positive feedback in endometrial cellsSphingosine kinase 1 is regulated by peroxisome proliferator-activated receptor α in response to free fatty acids and is essential for skeletal muscle interleukin-6 production and signaling in diet-induced obesity.Negative regulation of Stat3 by activating PTPN11 mutants contributes to the pathogenesis of Noonan syndrome and juvenile myelomonocytic leukemia.STAT3 transcription factor is constitutively activated and is oncogenic in nasal-type NK/T-cell lymphoma.Recent Advances and Challenges of mTOR Inhibitors Use in the Treatment of Patients with Tuberous Sclerosis Complex.Why did eukaryotes evolve only once? Genetic and energetic aspects of conflict and conflict mediation.Transcriptional response to circumscribed cortical brain ischemia: spatiotemporal patterns in ischemic vs. remote non-ischemic cortex.Opposite regulation of myc and p21waf1 transcription by STAT3 proteins.STAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug ResistanceDifferential activation of signaling pathways involved in cell death, survival and inflammation by radiocontrast media in human renal proximal tubular cells.The cdk5 kinase regulates the STAT3 transcription factor to prevent DNA damage upon topoisomerase I inhibition.12-O-tetradecanoylphorbol-13-acetate inhibits melanoma growth by inactivation of STAT3 through protein kinase C-activated tyrosine phosphatase(s)Physical and functional interactions between STAT3 and KAP1.Identification of de novo STAT3 target gene in liver regeneration.Novel involvement of the immunomodulator AS101 in IL-10 signaling, via the tyrosine kinase Fer.A New STAT3-binding Partner, ARL3, Enhances the Phosphorylation and Nuclear Accumulation of STAT3.Regulation of signal transduction and role of platelets in liver regenerationShear flow attenuates serum-induced STAT3 activation in endothelial cells.Interleukin-27 Protects Cardiomyocyte-Like H9c2 Cells against Metabolic Syndrome: Role of STAT3 Signaling.Proteolytic conversion of STAT3alpha to STAT3gamma in human neutrophils: role of granule-derived serine proteases.The catalytic activity of the eukaryotic initiation factor-2alpha kinase PKR is required to negatively regulate Stat1 and Stat3 via activation of the T-cell protein-tyrosine phosphatase.
P2860
Q26801053-37F0C0B6-2C43-4B14-B62B-1DFF85289090Q28262816-9FBED29C-0098-49F4-8131-4F5F857411E1Q28567562-5C22ED3B-C34F-4FE2-804E-BF42FEC453D2Q33196327-512764CA-B728-42F1-844D-E5D6942A414BQ34801318-39DCA651-E9DF-4994-9D9E-962DEF6C4B6EQ34962993-1BB14ECC-937C-4836-BCE5-450CC1DAA27CQ35006301-9D460F2D-6CC6-4FE1-AE60-65B02C503480Q35183021-EC7E83FF-A27B-4451-BE8E-3ACE1F92A393Q35347976-F072B6F9-139F-434D-AB66-8DC3F7ECB588Q35643695-AC8145F1-0056-4A1E-81C7-D4041113594CQ36031911-02E41EBC-C273-41C8-A64F-1877FBD09B27Q36116820-E66395F9-52F5-4AF5-BEE5-E32924DC7130Q36395710-8E9DFB1A-1FA1-4831-9336-24004169496FQ36497297-FEDD2E5C-E0F8-4B09-8915-9285F1F6D74DQ36714559-0B81731C-D600-4EB9-8F26-DE6DDE7AAE93Q36719279-1A1535C3-CB16-43DB-B4BF-79332BB7C5D3Q36843317-35B7FD9E-468F-4A87-8766-D0BF1E73FD8BQ36909958-F925BC55-7BD7-4F23-BB52-866749E08109Q37114996-7AD5EB65-9BD7-4847-B09F-37B9E62250E4Q37188615-0AF1ED70-FA52-434D-8453-30312BBCDA99Q37311833-4DE3B7DF-E730-47B3-94FB-7AB1B9E94BE3Q37372285-8EFE33A6-0786-4725-A7B5-A590AA7105D2Q37485330-E2820120-7ACC-48B1-8AE2-D2C352DF33E8Q37721031-6D3F1948-666E-42C5-89C6-893A8E730C7DQ38113552-B87AAAF9-5E6B-4145-BE5F-DB149A5B8D84Q38342560-CFB7C059-D7D0-4D04-9BF3-92C28F7C55BCQ38360847-C92CFDEC-5C55-4636-BC57-B0ED87F29425Q38536624-5B8568C1-ADC1-44C7-B085-80714560461EQ39637710-AD7D73B0-100B-4369-A852-F644C8161C41Q39697762-E6183AE6-205F-46D7-A657-A25A323DA1C5Q39799474-8BE7B5AD-7346-4DBD-96EA-48A93BA18E10Q40044888-CC2E6250-9A92-41CD-87BF-1156B137944DQ40049838-BEE863CB-469C-4875-8EB7-1C6D538EA5F5Q40150672-F0BDF58F-E3AD-4DB4-BBF1-ED8EFAA29ADDQ41984541-A1F169D9-A6F9-48B7-A1E3-BA5BB106EE92Q42234289-5AFD34F1-233C-450D-83A4-B8202EAA812BQ42438291-E4658D86-F506-4D73-B051-F9C5473C8D90Q42548054-730CA081-1C1B-4E60-BE42-E4E89B9D292BQ44897858-5AACD6BA-7190-4A87-ACB9-FAAF18E15737Q46907819-5D332933-C536-4C5C-911D-BFF0E7A540D6
P2860
description
im Mai 2002 veröffentlichter wissenschaftlicher Artikel
@de
наукова стаття, опублікована в травні 2002
@uk
name
What does Stat3 do?
@en
type
label
What does Stat3 do?
@en
prefLabel
What does Stat3 do?
@en
P356
P1476
What does Stat3 do?
@en
P2093
Chien-kuo Lee
David E. Levy
P304
P356
10.1172/JCI200215650
P407
P577
2002-05-01T00:00:00Z