Recombinant human Dnase I (rhDNase) in patients with lupus nephritis
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Disturbances of apoptotic cell clearance in systemic lupus erythematosusTreatment for lupus nephritisTargeted therapeutics in SLE: emerging strategies to modulate the interferon pathwayIntrapleural tissue plasminogen activator and deoxyribonuclease therapy for pleural infectionThe Role of Anti-DNA Antibodies in the Development of Lupus Nephritis: A Complementary, or Alternative, Viewpoint?Lupus and desoxyribonucleaseImpaired DNase1-mediated degradation of neutrophil extracellular traps is associated with acute thrombotic microangiopathies.Renal Dnase1 enzyme activity and protein expression is selectively shut down in murine and human membranoproliferative lupus nephritisThe role of neutrophils and NETosis in autoimmune and renal diseases.Therapy of systemic lupus erythematosus: new agents and new evidence.NETs: the missing link between cell death and systemic autoimmune diseases?Novel approaches in the treatment of lupus nephritis.Unintentional intramuscular administration of tPA/DNase for pleural infection.Therapy of systemic lupus erythematosus: a look into the futureThe in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosusTriggers for anti-chromatin autoantibody production in SLE.Acquired loss of renal nuclease activity is restricted to DNaseI and is an organ-selective feature in murine lupus nephritis.Antigen is required for maturation and activation of pathogenic anti-DNA antibodies and systemic inflammation.A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources.Autoimmunity versus tolerance: can dying cells tip the balance?Neutrophil Extracellular Traps Promote the Development and Progression of Liver Metastases after Surgical Stress.Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupusTargeting of the immune system in systemic lupus erythematosus.Pharmacotherapy of systemic lupus erythematosus.Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus.Chromatin as a target antigen in human and murine lupus nephritisClearing the complexity: immune complexes and their treatment in lupus nephritis.Lupus nephritis: enigmas, conflicting models and an emerging concept.Neutrophil extracellular traps in cancer progression.Antitumor Effects of Systemic DNAse I and Proteases in an In Vivo Model.Cell death in the pathogenesis of systemic lupus erythematosus and lupus nephritis.NETosis provides the link between activation of neutrophils on hemodialysis membrane and comorbidities in dialyzed patientsAn emerging role for neutrophil extracellular traps in noninfectious disease.In Vivo Role of Neutrophil Extracellular Traps in Antiphospholipid Antibody-Mediated Venous Thrombosis.5'-Phosphate oligodeoxynucleotides enhance the phosphodiester-CpG DNA-induced inflammatory response in macrophages.DNaseI protects against Paraquat-induced acute lung injury and pulmonary fibrosis mediated by mitochondrial DNA.Extracorporeal immunoadsorption of antibodies against the VRT-101 laminin epitope in systemic lupus erythematosus: a feasibility evaluation study.Pharmacologic Protection of Mitochondrial DNA Integrity May Afford a New Strategy for Suppressing Lung Ischemia-Reperfusion Injury.Lupus nephritis progression in FcγRIIB-/-yaa mice is associated with early development of glomerular electron dense deposits and loss of renal DNase I in severe disease.Therapeutic targeting of extracellular DNA improves the outcome of intestinal ischemic reperfusion injury in neonatal rats.
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Recombinant human Dnase I (rhDNase) in patients with lupus nephritis
description
im Januar 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 01 January 1999
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 1999
@uk
name
Recombinant human Dnase I (rhDNase) in patients with lupus nephritis
@en
Recombinant human Dnase I
@nl
type
label
Recombinant human Dnase I (rhDNase) in patients with lupus nephritis
@en
Recombinant human Dnase I
@nl
prefLabel
Recombinant human Dnase I (rhDNase) in patients with lupus nephritis
@en
Recombinant human Dnase I
@nl
P2093
P1433
P1476
Recombinant human Dnase I (rhDNase) in patients with lupus nephritis
@en
P2093
D Averthelyi
D Sinicropi
D T Boumpas
J H Klippel
P356
10.1191/096120399678847380
P577
1999-01-01T00:00:00Z