about
Molecular underpinnings of ventral surface chemoreceptor function: focus on KCNQ channelsExternal pH modulates EAG superfamily K+ channels through EAG-specific acidic residues in the voltage sensorRetrotrapezoid nucleus and parafacial respiratory group.Anesthetic activation of central respiratory chemoreceptor neurons involves inhibition of a THIK-1-like background K(+) current.Respiratory control by ventral surface chemoreceptor neurons in rats.Retrotrapezoid nucleus: a litmus test for the identification of central chemoreceptors.Regulation of ventral surface chemoreceptors by the central respiratory pattern generator.Purinergic P2 receptors modulate excitability but do not mediate pH sensitivity of RTN respiratory chemoreceptors.Expression of Phox2b by brainstem neurons involved in chemosensory integration in the adult rat.The retrotrapezoid nucleus and central chemoreception.TASK channels determine pH sensitivity in select respiratory neurons but do not contribute to central respiratory chemosensitivity.Serotonergic neurons activate chemosensitive retrotrapezoid nucleus neurons by a pH-independent mechanism.Current ideas on central chemoreception by neurons and glial cells in the retrotrapezoid nucleusPurinergic regulation of vascular tone in the retrotrapezoid nucleus is specialized to support the drive to breathe.Astrocyte chemoreceptors: mechanisms of H+ sensing by astrocytes in the retrotrapezoid nucleus and their possible contribution to respiratory drive.Astrocytes in the retrotrapezoid nucleus sense H+ by inhibition of a Kir4.1-Kir5.1-like current and may contribute to chemoreception by a purinergic mechanism.Purinergic signalling contributes to chemoreception in the retrotrapezoid nucleus but not the nucleus of the solitary tract or medullary raphe.HCN channels contribute to serotonergic modulation of ventral surface chemosensitive neurons and respiratory activityLeptin into the ventrolateral medulla facilitates chemorespiratory response in leptin-deficient (ob/ob) mice.Hyperoxia, reactive oxygen species, and hyperventilation: oxygen sensitivity of brain stem neurons.Nitric oxide activates hypoglossal motoneurons by cGMP-dependent inhibition of TASK channels and cGMP-independent activation of HCN channels.Purinergic receptor blockade in the retrotrapezoid nucleus attenuates the respiratory chemoreflexes in awake ratsCharacterization of the chemosensitive response of individual solitary complex neurons from adult ratsP2Y1 receptors expressed by C1 neurons determine peripheral chemoreceptor modulation of breathing, sympathetic activity, and blood pressure.Epilepsy-Associated KCNQ2 Channels Regulate Multiple Intrinsic Properties of Layer 2/3 Pyramidal NeuronsIndependent purinergic mechanisms of central and peripheral chemoreception in the rostral ventrolateral medulla.Facilitation of breathing by leptin effects in the central nervous system.AMP-activated protein kinase inhibits TREK channels.Connexin26 hemichannels with a mutation that causes KID syndrome in humans lack sensitivity to CO2.Glucose increases activity and Ca2+ in insulin-producing cells of adult Drosophila.KCNQ channels determine serotonergic modulation of ventral surface chemoreceptors and respiratory drive.Cholinergic control of ventral surface chemoreceptors involves Gq/inositol 1,4,5-trisphosphate-mediated inhibition of KCNQ channels.New advances in the neural control of breathing.Regulation of ventral surface CO2/H+-sensitive neurons by purinergic signalling.MeCP2 Deficiency Leads to Loss of Glial Kir4.1.Adenosine Signaling through A1 Receptors Inhibits Chemosensitive Neurons in the Retrotrapezoid NucleusDisordered breathing in a mouse model of Dravet syndromeBicarbonate directly modulates activity of chemosensitive neurons in the retrotrapezoid nucleusCholinergic neurons in the pedunculopontine tegmental nucleus modulate breathing in rats by direct projections to the retrotrapezoid nucleus
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Daniel K Mulkey
@ast
Daniel K Mulkey
@en
Daniel K Mulkey
@es
Daniel K Mulkey
@nl
type
label
Daniel K Mulkey
@ast
Daniel K Mulkey
@en
Daniel K Mulkey
@es
Daniel K Mulkey
@nl
prefLabel
Daniel K Mulkey
@ast
Daniel K Mulkey
@en
Daniel K Mulkey
@es
Daniel K Mulkey
@nl
P106
P1153
6701311810
P21
P31
P496
0000-0002-7040-3927