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Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoidsPhysical and enzymatic properties of a class III isozyme of human liver alcohol dehydrogenase: chi-ADHKinetics of human alcohol dehydrogenase with ring-oxidized retinoids: effect of Tween 80Retinoids, omega-hydroxyfatty acids and cytotoxic aldehydes as physiological substrates, and H2-receptor antagonists as pharmacological inhibitors, of human class IV alcohol dehydrogenaseHuman aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolismNovel alkenal/one reductase activity of yeast NADPH:quinone reductase Zta1p. Prospect of the functional role for the ζ-crystallin family.Characterization of a (2R,3R)-2,3-butanediol dehydrogenase as the Saccharomyces cerevisiae YAL060W gene product. Disruption and induction of the gene.Molecular basis for differential substrate specificity in class IV alcohol dehydrogenases: a conserved function in retinoid metabolism but not in ethanol oxidationThe Xenopus alcohol dehydrogenase gene family: characterization and comparative analysis incorporating amphibian and reptilian genomesFirst pass metabolism of ethanol is strikingly influenced by the speed of gastric emptying.Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase.Class III alcohol dehydrogenase from Saccharomyces cerevisiae: structural and enzymatic features differ toward the human/mammalian forms in a manner consistent with functional needs in formaldehyde detoxication.Aldo-keto reductases from the AKR1B subfamily: retinoid specificity and control of cellular retinoic acid levels.Pea formaldehyde-active class III alcohol dehydrogenase: common derivation of the plant and animal forms but not of the corresponding ethanol-active forms (classes I and P).Kinetic and structural evidence of the alkenal/one reductase specificity of human ζ-crystallin.Enantioselective Synthesis of Vicinal (R,R)-Diols by Saccharomyces cerevisiae Butanediol Dehydrogenase.Enzyme and isozyme developments within the medium-chain alcohol dehydrogenase family.Chemical modification by pyridoxal 5'-phosphate and cyclohexane-1,2-dione indicates that Lys-7 and Arg-10 are involved in the p2 phosphate-binding subsite of bovine pancreatic ribonuclease A.Human prostaglandin reductase 1 (PGR1): Substrate specificity, inhibitor analysis and site-directed mutagenesis.Biocatalytic production of alpha-hydroxy ketones and vicinal diols by yeast and human aldo-keto reductases.Aldo-keto reductases in retinoid metabolism: search for substrate specificity and inhibitor selectivity.Expression, localization and potential physiological significance of alcohol dehydrogenase in the gastrointestinal tract.S-nitrosoglutathione reductase activity of human and yeast glutathione-dependent formaldehyde dehydrogenase and its nuclear and cytoplasmic localisation.Complete reversal of coenzyme specificity by concerted mutation of three consecutive residues in alcohol dehydrogenase.Release of neurotransmitters from rat brain nerve terminals after chronic ethanol ingestion: differential effects in cortex and hippocampus.The specificity of alcohol dehydrogenase with cis-retinoids. Activity with 11-cis-retinol and localization in retina.Alcohol dehydrogenase isoenzymes in rat development. Effect of maternal ethanol consumption.Characterization of AKR1B16, a novel mouse aldo-keto reductase.Synthesis of enantiopure C3- and C4-hydroxyretinals and their enzymatic reduction by ADH8 from Xenopus laevis.Arabidopsis formaldehyde dehydrogenase. Molecular properties of plant class III alcohol dehydrogenase provide further insights into the origins, structure and function of plant class p and liver class I alcohol dehydrogenases.Structural basis for the inhibition of AKR1B10 by the C3 brominated TTNPB derivative UVI2008.The yeast ζ-crystallin/NADPH:quinone oxidoreductase (Zta1p) is under nutritional control by the target of rapamycin pathway and is involved in the regulation of argininosuccinate lyase mRNA half-life.Alcohol dehydrogenase of human and rat blood vessels. Role in ethanol metabolism.1H-NMR studies on the binding subsites of bovine pancreatic ribonuclease ANew human liver alcohol dehydrogenase forms with unique kinetic characteristicsSimian liver alcohol dehydrogenase: isolation and characterization of isoenzymes from Saimiri sciureusProperties of rat retina alcohol dehydrogenaseAction of metadoxine on isolated human and rat alcohol and aldehyde dehydrogenases. Effect on enzymes in chronic ethanol-fed ratsNucleotide binding and affinity labelling support the existence of the phosphate-binding subsite p2 in bovine pancreatic ribonuclease AMammalian alcohol dehydrogenase: characteristics of class III isoenzymes
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description
researcher ORCID: 0000-0002-5071-9465
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wetenschapper
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name
Xavier Parés
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Xavier Parés
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Xavier Parés
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Xavier Parés
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Xavier Parés
@en
Xavier Parés
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prefLabel
Xavier Parés
@ast
Xavier Parés
@en
Xavier Parés
@nl
P106
P21
P31
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0000-0002-5071-9465