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Archived unfrozen neonatal blood spots are amenable to quantitative gene expression analysis.Dicer expression exhibits a tissue-specific diurnal pattern that is lost during aging and in diabetes.Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation.Remodeling of retinal Fatty acids in an animal model of diabetes: a decrease in long-chain polyunsaturated fatty acids is associated with a decrease in fatty acid elongases Elovl2 and Elovl4.Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clockEffect of reduced retinal VLC-PUFA on rod and cone photoreceptorsRegulation of retinal inflammation by rhythmic expression of MiR-146a in diabetic retina.Global analysis of retina lipids by complementary precursor ion and neutral loss mode tandem mass spectrometry.A monophasic extraction strategy for the simultaneous lipidome analysis of polar and nonpolar retina lipidsComplementary precursor ion and neutral loss scan mode tandem mass spectrometry for the analysis of glycerophosphatidylethanolamine lipids from whole rat retina.Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase).Non-mammalian fat-1 gene prevents neoplasia when introduced to a mouse hepatocarcinogenesis model: Omega-3 fatty acids prevent liver neoplasia.N-3 polyunsaturated Fatty acids prevent diabetic retinopathy by inhibition of retinal vascular damage and enhanced endothelial progenitor cell reparative function.Changes in the daily rhythm of lipid metabolism in the diabetic retina.The unconventional role of acid sphingomyelinase in regulation of retinal microangiopathy in diabetic human and animal models.Wnting out ocular neovascularization: using nanoparticle delivery of very-low density lipoprotein receptor extracellular domain as Wnt pathway inhibitor in the retina.Imbalances in Mobilization and Activation of Pro-Inflammatory and Vascular Reparative Bone Marrow-Derived Cells in Diabetic Retinopathy.Per2 mutation recapitulates the vascular phenotype of diabetes in the retina and bone marrow.Tissue-specific, nutritional, and developmental regulation of rat fatty acid elongases.Hyperglycemia-induced reactive oxygen species toxicity to endothelial cells is dependent on paracrine mediatorsCarbon monoxide and nitric oxide mediate cytoskeletal reorganization in microvascular cells via vasodilator-stimulated phosphoprotein phosphorylation: evidence for blunted responsiveness in diabetesNovel mechanism for obesity-induced colon cancer progressionCNS inflammation and bone marrow neuropathy in type 1 diabetes.Glucose-specific regulation of aldose reductase in capan-1 human pancreatic duct cells In vitro.Role of Acid Sphingomyelinase in Shifting the Balance Between Proinflammatory and Reparative Bone Marrow Cells in Diabetic Retinopathy.Ataxia Telangiectasia Mutated Dysregulation Results in Diabetic RetinopathyAnalysis of Retina and Erythrocyte Glycerophospholipid Alterations in a Rat Model of Type 1 Diabetes.Aldose reductase meets histone acetylation: a new role for an old player.Differential regulation of high glucose-induced glyceraldehyde-3-phosphate dehydrogenase nuclear accumulation in Müller cells by IL-1beta and IL-6.Regulation of hepatic GLUT8 expression in normal and diabetic models.Increase in acid sphingomyelinase level in human retinal endothelial cells and CD34+ circulating angiogenic cells isolated from diabetic individuals is associated with dysfunctional retinal vasculature and vascular repair process in diabetes.Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in MiceELOVL4-Mediated Production of Very Long-Chain Ceramides Stabilizes Tight Junctions and Prevents Diabetes-Induced Retinal Vascular PermeabilityPlasma Exosomes Contribute to Microvascular Damage in Diabetic Retinopathy by Activating the Classical Complement PathwayDifferential composition of DHA and very-long-chain PUFAs in rod and cone photoreceptorsExtracellular Vesicle-Induced Classical Complement Activation Leads to Retinal Endothelial Cell Damage via MAC DepositionMicro-respirometry of whole cells and isolated mitochondriaDiurnal Rhythmicity of Autophagy Is Impaired in the Diabetic RetinaMitochondrial Ceramide Effects on the Retinal Pigment Epithelium in Diabetes
P50
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P50
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hulumtuese
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wetenschapper
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հետազոտող
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Julia V Busik
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Julia V Busik
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Julia V Busik
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Julia V Busik
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Julia V Busik
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Julia V Busik
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Julia V Busik
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Julia V Busik
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Julia V Busik
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Julia V Busik
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Julia V Busik
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Julia V Busik
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P106
P21
P31
P496
0000-0003-3453-7124