Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

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http://www.wikidata.org/entity/Q57374967
BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrateBAL1 and its partner E3 ligase, BBAP, link Poly(ADP-ribose) activation, ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage responseGene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.Are we ready to stratify treatment for diffuse large B-cell lymphoma using molecular hallmarks?Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemiaDiscovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencingTargeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesisCoordinated expression of microRNA-155 and predicted target genes in diffuse large B-cell lymphomaInactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphomaTumor microenvironments, the immune system and cancer survivalstam--a Bioconductor compliant R package for structured analysis of microarray data.Differential gene expression in HIV/SIV-associated and spontaneous lymphomas.Fatty acid oxidation and carnitine palmitoyltransferase I: emerging therapeutic targets in cancerNext-generation prognostic assessment for diffuse large B-cell lymphomaThe MYC/miR-17-92 axis in lymphoproliferative disorders: A common pathway with therapeutic potentialUnexpected functions of nuclear factor-κB during germinal center B-cell development: implications for lymphomagenesisThe genetic landscape of diffuse large B-cell lymphomaSystems analysis of high-throughput dataNovel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive reviewA phosphodiesterase 4B-dependent interplay between tumor cells and the microenvironment regulates angiogenesis in B-cell lymphoma.Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001Genes associated with the tumour microenvironment are differentially expressed in cured versus primary chemotherapy-refractory diffuse large B-cell lymphomaTargeting NF-kappaB in hematologic malignanciesBeyond RCHOP: A Blueprint for Diffuse Large B Cell Lymphoma Research.A microarray platform-independent classification tool for cell of origin class allows comparative analysis of gene expression in diffuse large B-cell lymphomaA mutant collagen XIII alters intestinal expression of immune response genes and predisposes transgenic mice to develop B-cell lymphomas.CluGene: A Bioinformatics Framework for the Identification of Co-Localized, Co-Expressed and Co-Regulated Genes Aimed at the Investigation of Transcriptional Regulatory Networks from High-Throughput Expression Data.Hierarchical gene selection and genetic fuzzy system for cancer microarray data classification.Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression dataPrediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets.Subclass mapping: identifying common subtypes in independent disease data sets.Diffuse large B-cell non-Hodgkin lymphoma involving the unilateral carotid space in an elderly man: A case report.Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancerHigh dose CHOP: a phase II study of initial treatment in aggressive non-Hodgkin lymphoma. Cancer and Leukemia Group B 9351.A phase I first-in-human study with tefinostat - a monocyte/macrophage targeted histone deacetylase inhibitor - in patients with advanced haematological malignancies.Data perturbation independent diagnosis and validation of breast cancer subtypes using clustering and patterns.Measuring similarity between gene expression profiles: a Bayesian approach.Immunophenotypic analysis of AIDS-related diffuse large B-cell lymphoma and clinical implications in patients from AIDS Malignancies Consortium clinical trials 010 and 034A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas.
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Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

Item
http://www.wikidata.org/entity/Q57374967
description
article
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im März 2005 veröffentlichter wissenschaftlicher Artikel
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wetenschappelijk artikel
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наукова стаття, опублікована в березні 2005
@uk
name
Molecular profiling of diffuse ...... by host inflammatory response
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Molecular profiling of diffuse ...... by host inflammatory response
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type
label
Molecular profiling of diffuse ...... by host inflammatory response
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Molecular profiling of diffuse ...... by host inflammatory response
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prefLabel
Molecular profiling of diffuse ...... by host inflammatory response
@en
Molecular profiling of diffuse ...... by host inflammatory response
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Molecular profiling of diffuse ...... by host inflammatory response
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10.1182/BLOOD-2004-07-2947
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