Residues within the myristoylation motif determine intracellular targeting of the neuronal Ca2+ sensor protein KChIP1 to post-ER transport vesicles and traffic of Kv4 K+ channels
about
Structural and functional deficits in a neuronal calcium sensor-1 mutant identified in a case of autistic spectrum disorderSall2 is a novel p75NTR-interacting protein that links NGF signalling to cell cycle progression and neurite outgrowthHigh-affinity interaction of the N-terminal myristoylation motif of the neuronal calcium sensor protein hippocalcin with phosphatidylinositol 4,5-bisphosphateThree-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamerThe diversity of calcium sensor proteins in the regulation of neuronal functionA VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channelsSpecific effects of KChIP3/calsenilin/DREAM, but not KChIPs 1, 2 and 4, on calcium signalling and regulated secretion in PC12 cellsNeuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signallingTraffic of Kv4 K+ channels mediated by KChIP1 is via a novel post-ER vesicular pathwayExpression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdalaMultiple promoters direct expression of three AKAP12 isoforms with distinct subcellular and tissue distribution profiles.Different KChIPs compete for heteromultimeric assembly with pore-forming Kv4 subunitsTrafficking of an endogenous potassium channel in adult ventricular myocytes.Auxiliary KChIP4a suppresses A-type K+ current through endoplasmic reticulum (ER) retention and promoting closed-state inactivation of Kv4 channelsFunctional stoichiometry underlying KChIP regulation of Kv4.2 functional expressionVisinin-like proteins (VSNLs): interaction partners and emerging functions in signal transduction of a subfamily of neuronal Ca2+ -sensor proteins.Convergent modulation of Kv4.2 channel alpha subunits by structurally distinct DPPX and KChIP auxiliary subunits.Modulatory mechanisms and multiple functions of somatodendritic A-type K (+) channel auxiliary subunitsUnderstanding the physiological roles of the neuronal calcium sensor proteins.Sense and specificity in neuronal calcium signalling.The myristoylation of guanylate cyclase-activating protein-2 causes an increase in thermodynamic stability in the presence but not in the absence of Ca²⁺.Gravin dynamics regulates the subcellular distribution of PKA.Multiple Kv channel-interacting proteins contain an N-terminal transmembrane domain that regulates Kv4 channel trafficking and gating.Model calcium sensors for network homeostasis: sensor and readout parameter analysis from a database of model neuronal networks.Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) mediates post-endocytic trafficking of protease-activated receptor 2 and calcitonin receptor-like receptor.Translocation of an endoproteolytically cleaved maxi-K channel isoform: mechanisms to induce human myometrial cell repolarization.Specificity, promiscuity and localization of ARF protein interactions with NCS-1 and phosphatidylinositol-4 kinase-III beta.Actin cytoskeleton-dependent regulation of corticotropin-releasing factor receptor heteromers.Interaction of neuronal calcium sensor-1 and ADP-ribosylation factor 1 allows bidirectional control of phosphatidylinositol 4-kinase beta and trans-Golgi network-plasma membrane traffic.Calcium-binding protein 1 is an inhibitor of agonist-evoked, inositol 1,4,5-trisphosphate-mediated calcium signaling.Identification of residues that determine the absence of a Ca(2+)/myristoyl switch in neuronal calcium sensor-1.Subcellular localization and transcription regulatory potency of KCNIP/Calsenilin/DREAM/KChIP proteins in cultured primary cortical neurons do not provide support for their role in CRE-dependent gene expression.Kv channel-interacting proteins as neuronal and non-neuronal calcium sensors
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Residues within the myristoylation motif determine intracellular targeting of the neuronal Ca2+ sensor protein KChIP1 to post-ER transport vesicles and traffic of Kv4 K+ channels
description
article
@en
im Dezember 2003 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в грудні 2003
@uk
name
Residues within the myristoyla ...... and traffic of Kv4 K+ channels
@en
Residues within the myristoyla ...... and traffic of Kv4 K+ channels
@nl
type
label
Residues within the myristoyla ...... and traffic of Kv4 K+ channels
@en
Residues within the myristoyla ...... and traffic of Kv4 K+ channels
@nl
prefLabel
Residues within the myristoyla ...... and traffic of Kv4 K+ channels
@en
Residues within the myristoyla ...... and traffic of Kv4 K+ channels
@nl
P356
P1476
Residues within the myristoyla ...... and traffic of Kv4 K+ channels
@en
P2093
D. W. O'Callaghan
P304
P356
10.1242/JCS.00803
P407
P577
2003-12-01T00:00:00Z