Cyclooxygenase-2–Derived Prostacyclin Regulates Arterial Thrombus Formation by Suppressing Tissue Factor in a Sirtuin-1–Dependent-Manner
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A Novel Antithrombotic Mechanism Mediated by the Receptors of the Kallikrein/Kinin and Renin-Angiotensin SystemsMyeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice.COX-2 protects against atherosclerosis independently of local vascular prostacyclin: identification of COX-2 associated pathways implicate Rgl1 and lymphocyte networks.LC-MS/MS confirms that COX-1 drives vascular prostacyclin whilst gene expression pattern reveals non-vascular sites of COX-2 expressionReduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factorProstacyclin analogue beraprost inhibits cardiac fibroblast proliferation depending on prostacyclin receptor activation through a TGF β-Smad signal pathway.An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair modeProtective effects of sirtuins in cardiovascular diseases: from bench to bedsideAngiotensin 1-7 and Mas decrease thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation.Obstructive sleep apnea syndrome: coagulation anomalies and treatment with continuous positive airway pressure.The contact activation and kallikrein/kinin systems: pathophysiologic and physiologic activities.Antithrombotic potential of the contact activation pathway.Sirtuins Expression and Their Role in Retinal Diseases.The Cardiovascular Pharmacology of Nonsteroidal Anti-Inflammatory Drugs.BDNFVal66met polymorphism: a potential bridge between depression and thrombosis.Brain-derived neurotrophic factor Val66Met polymorphism in depression and thrombosis: SIRT1 as a possible mediator.Role of prostacyclin signaling in endothelial production of soluble amyloid precursor protein-α in cerebral microvessels.
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P2860
Cyclooxygenase-2–Derived Prostacyclin Regulates Arterial Thrombus Formation by Suppressing Tissue Factor in a Sirtuin-1–Dependent-Manner
description
im September 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 03 August 2012
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована у вересні 2012
@uk
name
Cyclooxygenase-2–Derived Prost ...... n a Sirtuin-1–Dependent-Manner
@en
Cyclooxygenase-2–Derived Prost ...... n a Sirtuin-1–Dependent-Manner
@nl
type
label
Cyclooxygenase-2–Derived Prost ...... n a Sirtuin-1–Dependent-Manner
@en
Cyclooxygenase-2–Derived Prost ...... n a Sirtuin-1–Dependent-Manner
@nl
prefLabel
Cyclooxygenase-2–Derived Prost ...... n a Sirtuin-1–Dependent-Manner
@en
Cyclooxygenase-2–Derived Prost ...... n a Sirtuin-1–Dependent-Manner
@nl
P2093
P50
P1433
P1476
Cyclooxygenase-2-derived prost ...... n a sirtuin-1-dependent-manner
@en
P2093
Babette B Weksler
Elena Zacchi
Eva Tarantino
Fabrizio Veglia
Luciana Mussoni
Sara Gianellini
P304
P356
10.1161/CIRCULATIONAHA.112.097295
P407
P577
2012-08-03T00:00:00Z