Class-Switch Recombination (CSR)/Hyper-IgM (HIGM) Syndromes and Phosphoinositide 3-Kinase (PI3K) Defects

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Class-Switch Recombination (CSR)/Hyper-IgM (HIGM) Syndromes and Phosphoinositide 3-Kinase (PI3K) Defects

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wetenschappelijk artikel

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наукова стаття, опублікована у 2018

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name

Class-Switch Recombination (CS ...... sitide 3-Kinase (PI3K) Defects

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Class-Switch Recombination

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Item

label

Class-Switch Recombination (CS ...... sitide 3-Kinase (PI3K) Defects

@en

Class-Switch Recombination

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Class-Switch Recombination (CS ...... sitide 3-Kinase (PI3K) Defects

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Class-Switch Recombination

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P1476

Class-Switch Recombination (CS ...... sitide 3-Kinase (PI3K) Defects

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P2093

Cristiane J Nunes-Santos

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Jenna Bergerson

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Rekha D Jhamnani

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Sergio D Rosenzweig

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Creative Commons Attribution 4.0 International

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Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

P110delta, a novel phosphoinositide 3-kinase in leukocytes

p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes

Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage

IgH chain class switch recombination: mechanism and regulation

The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction

Update on the hyper immunoglobulin M syndromes

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2172

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scholarly article

review article

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10.3389/FIMMU.2018.02172

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English

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2018-01-01T00:00:00Z

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2018-09-26T00:00:00Z

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P698

30319630

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P921

Hyper IgM syndrome

globulins

blood proteins

P932

6168630

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