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(13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo.Dual-modality gene reporter for in vivo imaging.Oatp1 enhances bioluminescence by acting as a plasma membrane transporter for D-luciferinThe generation of a conditional reporter that enables bioluminescence imaging of Cre/loxP-dependent tumorigenesis in mice.Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia.Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis.Development of Timd2 as a reporter gene for MRICholine Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target.Bioluminescent imaging: a critical tool in pre-clinical oncology research.Imaging Mouse Models of Cancer.Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer.A quantitative FastFUCCI assay defines cell cycle dynamics at a single-cell level.The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis.Imaging sialylated tumor cell glycans in vivo.Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies.Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma.Versatile and enhanced tumour modelling in mice via somatic cell transduction.A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging.Noninvasive bioluminescence imaging of normal and spontaneously transformed prostate tissue in mice.Xenopus HDm, a maternally expressed histone deacetylase, belongs to an ancient family of acetyl-metabolizing enzymes.Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice.Irrigation of cutaneous squamous cell carcinoma wounds to prevent local recurrence.Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases[18F]fluoroethyltyrosine-induced Cerenkov Luminescence Improves Image-Guided Surgical Resection of Glioma.Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in miceA marker-independent lineage-tracing system to quantify clonal dynamics and stem cell functionality in cancer tissue
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0003-0139-6054
@en
name
Scott K Lyons
@ast
Scott K Lyons
@en
Scott K Lyons
@es
Scott K Lyons
@nl
type
label
Scott K Lyons
@ast
Scott K Lyons
@en
Scott K Lyons
@es
Scott K Lyons
@nl
prefLabel
Scott K Lyons
@ast
Scott K Lyons
@en
Scott K Lyons
@es
Scott K Lyons
@nl
P106
P108
P1153
7102022142
P31
P496
0000-0003-0139-6054