about
Wound repair: role of immune-epithelial interactionsIntestinal Antigen-Presenting Cells: Key Regulators of Immune Homeostasis and InflammationSmall intestinal intraepithelial TCRγδ+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitisSpecific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes.Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance.IFNγ-induced suppression of β-catenin signaling: evidence for roles of Akt and 14.3.3ζ.Lactobacillus rhamnosus (LGG) regulates IL-10 signaling in the developing murine colon through upregulation of the IL-10R2 receptor subunitDifferential induction of interleukin-10 and interleukin-12 in dendritic cells by microbial toll-like receptor activators and skewing of T-cell cytokine profiles.Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization.Phenotypic and functional profiling of mouse intestinal antigen presenting cells.Harnessing regulatory T cells for the treatment of inflammatory bowel disease.IL-36γ Transforms the Tumor Microenvironment and Promotes Type 1 Lymphocyte-Mediated Antitumor Immune Responses.A(₂B)AR expression in non-immune cells plays an important role in the development of murine colitisCutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage.The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair.Viral infection. Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18Macrophage Isolation from the Mouse Small and Large Intestine.Division of labor, plasticity, and crosstalk between dendritic cell subsets.The role of the vascular dendritic cell network in atherosclerosis.Neutrophils enlist IL-22 to restore order in the gutEffects of MF59 Adjuvant on Induction of Isotype-Switched IgG Antibodies and Protection after Immunization with T-Dependent Influenza Virus Vaccine in the Absence of CD4+ T Cells.Contribution of Mesenteric Lymph Nodes and GALT to the Intestinal Foxp3+ Regulatory T-Cell Compartment.Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity.Targeting intestinal inflammation with CD98 siRNA/PEI-loaded nanoparticles.Fab'-bearing siRNA TNFα-loaded nanoparticles targeted to colonic macrophages offer an effective therapy for experimental colitis.Neutrophil-derived JAML inhibits repair of intestinal epithelial injury during acute inflammation.IL-17A-mediated neutrophil recruitment limits expansion of segmented filamentous bacteria.CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice.Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling.Tbet and IL-36γ cooperate in therapeutic DC-mediated promotion of ectopic lymphoid organogenesis in the tumor microenvironment.IL-36γ signaling controls the induced regulatory T cell-Th9 cell balance via NFκB activation and STAT transcription factors.Negative selection of T cells by Helicobacter pylori as a model for bacterial strain selection by immune evasion.Expression of IL-10 receptors on epithelial cells from the murine small and large intestine.Acquired alkylating drug resistance of a human ovarian carcinoma cell line is unaffected by altered levels of pro- and anti-apoptotic proteins.Enhanced immune responses by skin vaccination with influenza subunit vaccine in young hosts.Hepatic stellate cells preferentially induce Foxp3+ regulatory T cells by production of retinoic acid.Isolation and characterization of dendritic cells and macrophages from the mouse intestine.Moving Beyond the Mouse: Key New Insight Into Human Colonic Dendritic CellsAdenosine triphosphate energizes intestinal T(H)17 cells.Matrix metalloproteinase MMP9 maintains epithelial barrier function and preserves mucosal lining in colitis associated cancer.
P50
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description
researcher ORCID ID = 0000-0002-1072-7444
@en
wetenschapper
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name
Timothy Luke Denning
@ast
Timothy Luke Denning
@en
Timothy Luke Denning
@es
Timothy Luke Denning
@nl
type
label
Timothy Luke Denning
@ast
Timothy Luke Denning
@en
Timothy Luke Denning
@es
Timothy Luke Denning
@nl
prefLabel
Timothy Luke Denning
@ast
Timothy Luke Denning
@en
Timothy Luke Denning
@es
Timothy Luke Denning
@nl
P106
P1153
6602173849
P31
P496
0000-0002-1072-7444