Balancing of Histone H3K4 Methylation States by the Kdm5c/SMCX Histone Demethylase Modulates Promoter and Enhancer Function
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Histone demethylases in chromatin biology and beyondKDM5 interacts with Foxo to modulate cellular levels of oxidative stressDeciphering the Epigenetic Code in Embryonic and Dental Pulp Stem CellsHistone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genesScreen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistanceThe KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiationThe histone demethylase KDM3A regulates the transcriptional program of the androgen receptor in prostate cancer cells.Histone lysine demethylases in mammalian embryonic development.Histone demethylation maintains Prdm14 and Tsix expression and represses xIst in embryonic stem cells.Epigenetic memory gained by priming with osteogenic induction medium improves osteogenesis and other properties of mesenchymal stem cells.Lysine-specific demethylase 5C promotes hepatocellular carcinoma cell invasion through inhibition BMP7 expression.Disrupted intricacy of histone H3K4 methylation in neurodevelopmental disorders.Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair.Mutations in the KDM5C ARID Domain and Their Plausible Association with Syndromic Claes-Jensen-Type Disease.Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer.Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.A Mouse Model of X-linked Intellectual Disability Associated with Impaired Removal of Histone MethylationSuppression of Enhancer Overactivation by a RACK7-Histone Demethylase ComplexHistone H3 lysine 4 methyltransferases and demethylases in self-renewal and differentiation of stem cells.Histone methylation during neural development.Intrinsic regulations in neural fate commitment.XCI-escaping gene KDM5C contributes to ovarian development via downregulating miR-320a.Histone H3K4 trimethylation: dynamic interplay with pre-mRNA splicing.Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs.Enhancer deregulation in cancer and other diseases.The Histone Demethylase KDM5 Activates Gene Expression by Recognizing Chromatin Context through Its PHD Reader Motif.New Insights Into Intellectual Disability Caused by Mutations in a Chromatin Regulator.Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme.Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice.Loss of Kdm5c Causes Spurious Transcription and Prevents the Fine-Tuning of Activity-Regulated Enhancers in Neurons.DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism.Identification of H3K4me1-associated proteins at mammalian enhancers.JARID1 Histone Demethylases: Emerging Targets in Cancer.A Drosophila Model of Intellectual Disability Caused by Mutations in the Histone Demethylase KDM5.Altered Gene-Regulatory Function of KDM5C by a Novel Mutation Associated With Autism and Intellectual Disability.Targeting JARID1B's demethylase activity blocks a subset of its functions in oral cancer.Esrrb extinction triggers dismantling of naïve pluripotency and marks commitment to differentiation
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Balancing of Histone H3K4 Methylation States by the Kdm5c/SMCX Histone Demethylase Modulates Promoter and Enhancer Function
description
im März 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 28 March 2013
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована у квітні 2013
@uk
name
Balancing of Histone H3K4 Meth ...... Promoter and Enhancer Function
@en
Balancing of Histone H3K4 Meth ...... Promoter and Enhancer Function
@nl
type
label
Balancing of Histone H3K4 Meth ...... Promoter and Enhancer Function
@en
Balancing of Histone H3K4 Meth ...... Promoter and Enhancer Function
@nl
prefLabel
Balancing of Histone H3K4 Meth ...... Promoter and Enhancer Function
@en
Balancing of Histone H3K4 Meth ...... Promoter and Enhancer Function
@nl
P2093
P50
P1433
P1476
Balancing of histone H3K4 meth ...... promoter and enhancer function
@en
P2093
Dik van Leenen
Frank C P Holstege
Frank G Grosveld
H T Marc Timmers
Nikolay S Outchkourov
P304
P356
10.1016/J.CELREP.2013.02.030
P577
2013-03-28T00:00:00Z