about
Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystalsGating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallographyHomodimerization of the Src homology 3 domain of the calcium channel β-subunit drives dynamin-dependent endocytosis.Bridging the gap between structural models of nicotinic receptor superfamily ion channels and their corresponding functional statesThe atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold.The guanylate kinase domain of the beta-subunit of voltage-gated calcium channels suffices to modulate gating.Slow inactivation in Shaker K channels is delayed by intracellular tetraethylammonium.Mutations of nonconserved residues within the calcium channel alpha1-interaction domain inhibit beta-subunit potentiation.Chasing the open-state structure of pentameric ligand-gated ion channels.Swapping the I-II intracellular linker between L-type CaV1.2 and R-type CaV2.3 high-voltage gated calcium channels exchanges activation attributes.The alpha1-beta-subunit interaction that modulates calcium channel activity is reversible and requires a competent alpha-interaction domain.Functional Role of Solvent Entropy and Conformational Entropy of Metal Binding in a Dynamically Driven Allosteric SystemDesensitization of neurotransmitter-gated ion channels during high-frequency stimulation: a comparative study of Cys-loop, AMPA and purinergic receptorsSmall-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases
P50
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P50
description
researcher ORCID ID = 0000-0002-1044-943X
@en
wetenschapper
@nl
name
Giovanni Gonzalez-Gutierrez
@ast
Giovanni Gonzalez-Gutierrez
@en
Giovanni Gonzalez-Gutierrez
@es
Giovanni Gonzalez-Gutierrez
@nl
type
label
Giovanni Gonzalez-Gutierrez
@ast
Giovanni Gonzalez-Gutierrez
@en
Giovanni Gonzalez-Gutierrez
@es
Giovanni Gonzalez-Gutierrez
@nl
prefLabel
Giovanni Gonzalez-Gutierrez
@ast
Giovanni Gonzalez-Gutierrez
@en
Giovanni Gonzalez-Gutierrez
@es
Giovanni Gonzalez-Gutierrez
@nl
P106
P21
P31
P496
0000-0002-1044-943X