about
Flipping of alkylated DNA damage bridges base and nucleotide excision repairDNA mismatch repair and mutation avoidance pathwaysSchizosaccharomyces pombe MutSα and MutLα Maintain Stability of Tetra-Nucleotide Repeats and Msh3 of Hepta-Nucleotide Repeats.Deoxynucleoside Salvage in Fission Yeast Allows Rescue of Ribonucleotide Reductase Deficiency but Not Spd1-Mediated Inhibition of Replication.Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination.The msh2 gene of Schizosaccharomyces pombe is involved in mismatch repair, mating-type switching, and meiotic chromosome organization.Requirement for Msh6, but not for Swi4 (Msh3), in Msh2-dependent repair of base-base mismatches and mononucleotide loops in Schizosaccharomyces pombeDNA repair.Translesion DNA synthesis: little fingers teach tolerance.Identification of two mismatch-binding activities in protein extracts of Schizosaccharomyces pombe.Spd1 accumulation causes genome instability independently of ribonucleotide reductase activity but functions to protect the genome when deoxynucleotide pools are elevated.AtRAD1, a plant homologue of human and yeast nucleotide excision repair endonucleases, is involved in dark repair of UV damages and recombination.Mutagenesis of the HMGB (high-mobility group B) protein Cmb1 (cytosine-mismatch binding 1) of Schizosaccharomyces pombe: effects on recognition of DNA mismatches and damage.Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms.Elp3 and Dph3 of Schizosaccharomyces pombe mediate cellular stress responses through tRNALysUUU modifications.Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast.Ddb1 controls genome stability and meiosis in fission yeast.The mutator gene swi8 effects specific mutations in the mating-type region of Schizosaccharomyces pombe.Switching gene swi6, involved in repression of silent mating-type loci in fission yeast, encodes a homologue of chromatin-associated proteins from Drosophila and mammals.Role of the DNA repair nucleases Rad13, Rad2 and Uve1 of Schizosaccharomyces pombe in mismatch correction.A mutated dph3 gene causes sensitivity of Schizosaccharomyces pombe cells to cytotoxic agents.The mating-type region of Schizosaccharomyces pombe contains an essential gene encoding a protein homologous to human modulators of HIV transactivation.Spd2 assists Spd1 in the modulation of ribonucleotide reductase architecture but does not regulate deoxynucleotide pools.Genetic and cytological characterization of the RecA-homologous proteins Rad51 and Dmc1 of Schizosaccharomyces pombe.Different frameshift mutation spectra in non-repetitive DNA of MutSα- and MutLα-deficient fission yeast cellsSchizosaccharomyces pombe exo1 is involved in the same mismatch repair pathway as msh2 and pms1Hyperspeckled mutants of Schizosaccharomyces pombe: frequent mating-type switching without detectable double-strand breaksA mutated swi4 gene causes duplications in the mating-type region of Schizosaccharomyces pombe
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0003-0550-6513
@en
name
Oliver Fleck
@ast
Oliver Fleck
@en
Oliver Fleck
@es
Oliver Fleck
@nl
type
label
Oliver Fleck
@ast
Oliver Fleck
@en
Oliver Fleck
@es
Oliver Fleck
@nl
prefLabel
Oliver Fleck
@ast
Oliver Fleck
@en
Oliver Fleck
@es
Oliver Fleck
@nl
P106
P1153
6603818493
P21
P31
P496
0000-0003-0550-6513