Evidence for a Novel X-Linked Modifier Locus for Leber Hereditary Optic Neuropathy
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Leber hereditary optic neuropathy: current perspectivesThe background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicityHistorical perspective on mitochondrial medicinePure and syndromic optic atrophy explained by deep intronic OPA1 mutations and an intralocus modifierTreatment strategies for inherited optic neuropathies: past, present and futureFrom the laboratory to the clinic: molecular genetic testing in pediatric ophthalmology.Low penetrance of Leber's hereditary optic neuropathy in ten Han Chinese families carrying the ND6 T11484C mutationEvaluation of the X-linked modifier loci for Leber hereditary optic neuropathy with the G11778A mutation in ChineseVariation in OPA1 does not explain the incomplete penetrance of Leber hereditary optic neuropathy.Very high penetrance and occurrence of Leber's hereditary optic neuropathy in a large Han Chinese pedigree carrying the ND4 G11778A mutation.Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies.Profiling the mitochondrial proteome of Leber's Hereditary Optic Neuropathy (LHON) in Thailand: down-regulation of bioenergetics and mitochondrial protein quality control pathways in fibroblasts with the 11778G>A mutationThe optic nerve: a "mito-window" on mitochondrial neurodegenerationThe neuro-ophthalmology of mitochondrial diseaseMitochondrial-nuclear epistasis: implications for human aging and longevity.Oestrogens ameliorate mitochondrial dysfunction in Leber's hereditary optic neuropathy.Leber's hereditary optic neuropathy affects only female matrilineal relatives in two Chinese families.Mito-nuclear co-evolution: the positive and negative sides of functional ancient mutationsEfficient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy.LHON: Mitochondrial Mutations and More.Epigenetics, epidemiology and mitochondrial DNA diseases.Disorders of the optic nerve in mitochondrial cytopathies: new ideas on pathogenesis and therapeutic targets.Multiplex MALDI-TOF MS detection of mitochondrial variants in Brazilian patients with hereditary optic neuropathyCigarette toxicity triggers Leber's hereditary optic neuropathy by affecting mtDNA copy number, oxidative phosphorylation and ROS detoxification pathwaysInherited mitochondrial optic neuropathies.Reversing mother's curse: selection on male mitochondrial fitness effects.Gene-environment interactions in Leber hereditary optic neuropathy.Leber hereditary optic neuropathy: bad habits, bad vision?Evidence for nuclear modifier gene in mitochondrial cardiomyopathy.Treatment of hereditary optic neuropathies.Mitochondrial optic neuropathies: our travels from bench to bedside and back again.Sex disparities in neuro-ophthalmologic disorders.The X-Linked Hypothesis of Brain Disorders: Can Gender Ratios Tell Us Anything About Cellular Etiology of Neurodegenerative and Psychiatric Diseases?Genetics of Primary Inherited Disorders of the Optic Nerve: Clinical Applications.Leber Hereditary Optic Neuropathy: Bringing the Lab to the Clinic.Idebenone: A Review in Leber's Hereditary Optic Neuropathy.The exome sequencing identified the mutation in YARS2 encoding the mitochondrial tyrosyl-tRNA synthetase as a nuclear modifier for the phenotypic manifestation of Leber's hereditary optic neuropathy-associated mitochondrial DNA mutation.Targeting estrogen receptor β as preventive therapeutic strategy for Leber's hereditary optic neuropathy.Leber hereditary optic neuropathy: bridging the translational gap.Leber Hereditary Optic Neuropathy: A Mitochondrial Disease Unique in Many Ways.
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P2860
Evidence for a Novel X-Linked Modifier Locus for Leber Hereditary Optic Neuropathy
description
article
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wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2008
@uk
name
Evidence for a Novel X-Linked Modifier Locus for Leber Hereditary Optic Neuropathy
@en
Evidence for a Novel X-Linked Modifier Locus for Leber Hereditary Optic Neuropathy
@nl
type
label
Evidence for a Novel X-Linked Modifier Locus for Leber Hereditary Optic Neuropathy
@en
Evidence for a Novel X-Linked Modifier Locus for Leber Hereditary Optic Neuropathy
@nl
prefLabel
Evidence for a Novel X-Linked Modifier Locus for Leber Hereditary Optic Neuropathy
@en
Evidence for a Novel X-Linked Modifier Locus for Leber Hereditary Optic Neuropathy
@nl
P2093
P2860
P50
P1433
P1476
Evidence for a novel x-linked modifier locus for leber hereditary optic neuropathy
@en
P2093
Alfredo A Sadun
Solange R Salomao
Stephen P Daiger
Suma P Shankar
Terri A Braun
Terri M King
P2860
P356
10.1080/13816810701867607
P50
P577
2008-03-01T00:00:00Z