Response to Neoadjuvant Chemotherapy in Breast Cancer Could be Predictable by Measuring a Novel Serum Apoptosis Product, Caspase-Cleaved Cytokeratin 18: A Prospective Pilot Study - Wikidata - wikimedia - TriplyDB

Response to Neoadjuvant Chemotherapy in Breast Cancer Could be Predictable by Measuring a Novel Serum Apoptosis Product, Caspase-Cleaved Cytokeratin 18: A Prospective Pilot Study

Response to Neoadjuvant Chemotherapy in Breast Cancer Could be Predictable by Measuring a Novel Serum Apoptosis Product, Caspase-Cleaved Cytokeratin 18: A Prospective Pilot Study

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Elevation of serum fortilin levels is specific for apoptosis and signifies cell death in vivo.Chemotherapy increases caspase-cleaved cytokeratin 18 in the serum of breast cancer patients Biomarker method validation in anticancer drug development Clinical evaluation of M30 and M65 ELISA cell death assays as circulating biomarkers in a drug-sensitive tumor, testicular cancer.Circulating biomarkers of cell death after treatment with the BH-3 mimetic ABT-737 in a preclinical model of small-cell lung cancer.Circulating Levels of M30 and M65 Molecules in Transitional Cell Carcinoma of the Bladder and Their Relation to Tumor Progression.Investigation of bendamustine HCL in a phase 2 study in women with resistant ovarian cancer.Utilization of cytokeratin-based biomarkers for pharmacodynamic studies.Serum efficacy biomarkers for oncology.Apoptosis: why and how does it occur in biology?The M30 assay does not detect apoptosis in epithelial-derived cancer cells expressing low levels of cytokeratin 18.Methods to Evaluate Cell Growth, Viability, and Response to Treatment in a Tissue Engineered Breast Cancer Model.A high serum level of M65 is associated with tumour aggressiveness and an unfavourable prognosis for epithelial ovarian cancer.Safety, pharmacokinetics, and pharmacodynamics of the DR5 antibody LBY135 alone and in combination with capecitabine in patients with advanced solid tumors.Prognostic value and clinicopathological significance of serum- and tissue-based cytokeratin 18 express level in breast cancer: a meta-analysis.Clinical significance of serum M30 and M65 levels in metastatic pancreatic adenocarcinoma.

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Response to Neoadjuvant Chemotherapy in Breast Cancer Could be Predictable by Measuring a Novel Serum Apoptosis Product, Caspase-Cleaved Cytokeratin 18: A Prospective Pilot Study

http://www.wikidata.org/entity/Q57725217

description

article

@en

im Januar 2006 veröffentlichter wissenschaftlicher Artikel

@de

wetenschappelijk artikel

@nl

наукова стаття, опублікована в січні 2006

@uk

name

Response to Neoadjuvant Chemot ...... 18: A Prospective Pilot Study

@en

Response to Neoadjuvant Chemot ...... 18: A Prospective Pilot Study

@nl

type

label

Response to Neoadjuvant Chemot ...... 18: A Prospective Pilot Study

@en

Response to Neoadjuvant Chemot ...... 18: A Prospective Pilot Study

@nl

prefLabel

Response to Neoadjuvant Chemot ...... 18: A Prospective Pilot Study

@en

Response to Neoadjuvant Chemot ...... 18: A Prospective Pilot Study

@nl

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07357900600981307

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Cancer Investigation

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Response to neoadjuvant chemot ...... 18: a prospective pilot study

@en

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Engin Engin Ulukaya

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Murat Arslan

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Mutlu Demiray

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Osman Manavoglu

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Ozlem Saraydaroglu

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Sehsuvar Gokgoz

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Turkkan Evrensel

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Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

A novel assay for discovery and characterization of pro-apoptotic drugs and for monitoring apoptosis in patient sera.

A novel high-through-put assay for screening of pro-apoptotic drugs.

Primary chemotherapy to avoid mastectomy in tumors with diameters of three centimeters or more.

Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis.

Differentiation between cell death modes using measurements of different soluble forms of extracellular cytokeratin 18.

Mechanisms of cytotoxicity caused by antitumour drugs.

Primary chemotherapy in breast invasive carcinoma: predictive value of the immunohistochemical detection of hormonal receptors, p53, c-erbB-2, MiB1, pS2 and GST pi.

Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis

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669-676

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scholarly article

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10.1080/07357900600981307

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7

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24

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2006-11-01T00:00:00Z

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17118776

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