BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
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Cell cycle-specific function of Ikaros in human leukemiaMusashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemiaAcute lymphoblastic leukaemiaSelective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of IkarosAn allele of IKZF1 (Ikaros) conferring susceptibility to childhood acute lymphoblastic leukemia protects against type 1 diabetesdbCRID: a database of chromosomal rearrangements in human diseasesChemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome-positive acute lymphoblastic leukemiaRole of Ikaros in T-cell acute lymphoblastic leukemiaDNA sequencing of a cytogenetically normal acute myeloid leukaemia genomeImmunologically silent cancer clone transmission from mother to offspringThe Philadelphia chromosome in leukemogenesisNew Developments in Chronic Myeloid Leukemia: Implications for TherapyMouse models for radiation-induced cancersNew and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemiaGenetic abnormalities associated with acute lymphoblastic leukemiaEmerging technologies in paediatric leukaemiaZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid MalignanciesLong-Range Regulation of V(D)J RecombinationNovel agents and biomarkers for acute lymphoid leukemiaGenomic profiling of B-progenitor acute lymphoblastic leukemiaMicroRNAs in B cell development and malignancyRedefining ALL classification: toward detecting high-risk ALL and implementing precision medicineA health-care system perspective on implementing genomic medicine: pediatric acute lymphoblastic leukemia as a paradigmMouse models for efficacy testing of agents against radiation carcinogenesis—a literature reviewCurrent concepts in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemiaNovel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL.Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia.The Ikaros family of zinc-finger proteinsZebrafish Models of Human Leukemia: Technological Advances and Mechanistic InsightsChildhood acute lymphoblastic leukemia: Integrating genomics into therapyPrognostification of ALL by CytogeneticsCongenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the Ikaros geneLoci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemiaCo-existence of IL7R high and SH2B3 low expression distinguishes a novel high-risk acute lymphoblastic leukemia with Ikaros dysfunctionChallenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutationsUse of single nucleotide polymorphism array technology to improve the identification of chromosomal lesions in leukemiaA target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALLData Mining Approaches for Genomic Biomarker Development: Applications Using Drug Screening Data from the Cancer Genome Project and the Cancer Cell Line Encyclopedia
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BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
description
article publié dans la revue scientifique Nature
@fr
scientific article published in Nature
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wetenschappelijk artikel
@nl
наукова стаття, опублікована в Nature у квітні 2008
@uk
name
BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
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BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
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type
label
BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
@en
BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
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prefLabel
BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
@en
BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
@nl
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P356
P1433
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BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
@en
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Charles G. Mullighan
Christopher B. Miller
Ina Radtke
James Dalton
James R. Downing
Letha A. Phillips
Mary V. Relling
Michelle M. Le Beau
Sheila A. Shurtleff
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P2888
P304
P356
10.1038/NATURE06866
P407
P577
2008-04-13T00:00:00Z
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1052983633