A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins

A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins

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http://www.wikidata.org/entity/Q57776797
Structure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans.Shaping mycolactone for therapeutic use against inflammatory disorders.Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation.Mycolactone subverts immunity by selectively blocking the Sec61 translocon.History, biology and chemistry of Mycobacterium ulcerans infections (Buruli ulcer disease).Pleiotropic molecular effects of the Mycobacterium ulcerans virulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer.Recent advances: role of mycolactone in the pathogenesis and monitoring of Mycobacterium ulcerans infection/Buruli ulcer disease.Natural product analogues: towards a blueprint for analogue-focused synthesis.Boron chemistry in a new light.The chemistry and biology of mycolactones.Synthesis of deoxyelephantopin analogues.The potent effect of mycolactone on lipid membranes.Synthesis of the octahydronaphthalene core of nahuoic acid A via a B(C6F5)3-catalyzed intramolecular Diels-Alder (IMDA) reaction.Modular total syntheses of mycolactone A/B and its [2H]-isotopologueSynthetic strategies towards mycolactone A/B, an exotoxin secreted by Mycobacterium ulceransSynthesis of the Conjugated Tetraene Acid Side Chain of Mycolactone E by Suzuki-Miyaura Cross-Coupling Reaction of Alkenyl Boronates
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A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins

Item
http://www.wikidata.org/entity/Q57776797
description
im November 2011 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в листопаді 2011
@uk
name
A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins
@en
A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins
@nl
type
label
A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins
@en
A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins
@nl
prefLabel
A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins
@en
A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
A Diverted Total Synthesis of Mycolactone Analogues: An Insight into Buruli Ulcer Toxins
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921