Molecular insight into amyloid oligomer destabilizing mechanism of flavonoid derivative 2-(4′ benzyloxyphenyl)-3-hydroxy-chromen-4-one through docking and molecular dynamics simulations

Molecular insight into amyloid oligomer destabilizing mechanism of flavonoid derivative 2-(4′ benzyloxyphenyl)-3-hydroxy-chromen-4-one through docking and molecular dynamics simulations

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http://www.wikidata.org/entity/Q57781259
Molecular insights into Aβ42 protofibril destabilization with a fluorinated compound D744: A molecular dynamics simulation study.Nonequilibrium all-atom molecular dynamics simulation of the bubble cavitation and application to dissociate amyloid fibrils.Potential of mean force and molecular dynamics study on the transient interactions between α and β synuclein that drive inhibition of α-synuclein aggregation.NSAIDs as potential treatment option for preventing amyloid β toxicity in Alzheimer's disease: an investigation by docking, molecular dynamics, and DFT studies.Scrutiny of the mechanism of small molecule inhibitor preventing conformational transition of amyloid-β42 monomer: insights from molecular dynamics simulations.Conformational Dynamics and Stability of U-Shaped and S-Shaped Amyloid β Assemblies.Molecular dynamics simulations of lysozyme-lipid systems: probing the early steps of protein aggregation.Scrutiny of chain-length and N-terminal effects in α-helix folding: a molecular dynamics study on polyalanine peptides.Changing paradigm from one target one ligand towards multi target directed ligand design for key drug targets of Alzheimer disease: An important role of Insilco methods in multi target directed ligands design.The role of phenolic OH groups of flavonoid compounds with H-bond formation ability to suppress amyloid mature fibrils by destabilizing β-sheet conformation of monomeric Aβ17-42.
P2860

Molecular insight into amyloid oligomer destabilizing mechanism of flavonoid derivative 2-(4′ benzyloxyphenyl)-3-hydroxy-chromen-4-one through docking and molecular dynamics simulations

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http://www.wikidata.org/entity/Q57781259
description
article
@en
im Oktober 2015 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в жовтні 2015
@uk
name
Molecular insight into amyloid ...... ism of flavonoid derivative 2-
@nl
Molecular insight into amyloid ...... molecular dynamics simulations
@en
type
label
Molecular insight into amyloid ...... ism of flavonoid derivative 2-
@nl
Molecular insight into amyloid ...... molecular dynamics simulations
@en
prefLabel
Molecular insight into amyloid ...... ism of flavonoid derivative 2-
@nl
Molecular insight into amyloid ...... molecular dynamics simulations
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
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P1433
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Molecular insight into amyloid ...... molecular dynamics simulations
@en
P2093
P2860
P304
P31
P356
10.1080/07391102.2015.1074943
P433
P478
P50
P577
P698