about
Organization and function of the small Tim complexes acting along the import pathway of metabolite carriers into mammalian mitochondriaTim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell deathMultiple pathways for sorting mitochondrial precursor proteinsMdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery.An essential role of Sam50 in the protein sorting and assembly machinery of the mitochondrial outer membrane.Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria.The J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase.Sam35 of the mitochondrial protein sorting and assembly machinery is a peripheral outer membrane protein essential for cell viability.Signal recognition initiates reorganization of the presequence translocase during protein import.The mitochondrial ADP/ATP carrier associates with the inner membrane presequence translocase in a stoichiometric manner.Role of Tim21 in mitochondrial translocation contact sites.Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins.Mitochondrial protein import motor: differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase.Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes.Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors.NMR analyses on the interactions of the yeast Tim50 C-terminal region with the presequence and Tim50 core domain.The import motor of the yeast mitochondrial TIM23 preprotein translocase contains two different J proteins, Tim14 and Mdj2.Conserved N-terminal negative charges in the Tim17 subunit of the TIM23 translocase play a critical role in the import of preproteins into mitochondria.The Import of Proteins into the Mitochondrion of Toxoplasma gondiiDisorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genesEffect of mutations in Tom40 on stability of the translocase of the outer mitochondrial membrane (TOM) complex, assembly of Tom40, and import of mitochondrial preproteins.Methylation-controlled J-protein MCJ acts in the import of proteins into human mitochondria.Conserved and novel functions for Arabidopsis thaliana MIA40 in assembly of proteins in mitochondria and peroxisomesOxidative protein biogenesis and redox regulation in the mitochondrial intermembrane space.The protein translocation systems in plants - composition and variability on the example of Solanum lycopersicumEvidence of evolutionary constraints that influences the sequence composition and diversity of mitochondrial matrix targeting signalsIn vivo protein-interaction mapping of a mitochondrial translocator protein Tom22 at workTim50's presequence receptor domain is essential for signal driven transport across the TIM23 complexMitochondrial import and the twin-pore translocase.Mitochondrial assembly: protein import.Cooperation of translocase complexes in mitochondrial protein import.Protein import into mitochondria: origins and functions today (review).Oxa1/Alb3/YidC system for insertion of membrane proteins in mitochondria, chloroplasts and bacteria (review).Tim62, a Novel Mitochondrial Protein in Trypanosoma brucei, Is Essential for Assembly and Stability of the TbTim17 Protein Complex.Tim50 in Trypanosoma brucei possesses a dual specificity phosphatase activity and is critical for mitochondrial protein import.A dynamic machinery for import of mitochondrial precursor proteins.Diverse mechanisms and machineries for import of mitochondrial proteins.Multiple pathways for mitochondrial protein traffic.Two distinct membrane potential-dependent steps drive mitochondrial matrix protein translocation.Import of ribosomal proteins into yeast mitochondria.
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P2860
description
im November 2002 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в листопаді 2002
@uk
name
The Mitochondrial Presequence Translocase
@en
The Mitochondrial Presequence Translocase
@nl
type
label
The Mitochondrial Presequence Translocase
@en
The Mitochondrial Presequence Translocase
@nl
prefLabel
The Mitochondrial Presequence Translocase
@en
The Mitochondrial Presequence Translocase
@nl
P2093
P1433
P1476
The Mitochondrial Presequence Translocase
@en
P2093
Albert Sickmann
Andreas Geissler
Helmut E. Meyer
Katrin Brandner
Kaye N. Truscott
Nikolaus Pfanner
Nils Wiedemann
Peter Rehling
P304
P356
10.1016/S0092-8674(02)01073-5
P407
P577
2002-11-01T00:00:00Z