about
Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancerBS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathwayA novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumorsOPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation.Epigenomic and Functional Characterization of Junctophilin 3 (JPH3) as a Novel Tumor Suppressor Being Frequently Inactivated by Promoter CpG Methylation in Digestive Cancers.Apolipoprotein M gene (APOM) polymorphism modifies metabolic and disease traits in type 2 diabetes.Dickkopf-related protein 2 induces G0/G1 arrest and apoptosis through suppressing Wnt/β-catenin signaling and is frequently methylated in breast cancer.The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating WNT/β-catenin signaling and is frequently silenced in multiple tumors.The ubiquitin peptidase UCHL1 induces G0/G1 cell cycle arrest and apoptosis through stabilizing p53 and is frequently silenced in breast cancer.The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma.Zinc-finger protein 545 inhibits cell proliferation as a tumor suppressor through inducing apoptosis and is disrupted by promoter methylation in breast cancer.Double restriction-enzyme digestion improves the coverage and accuracy of genome-wide CpG methylation profiling by reduced representation bisulfite sequencing.The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas.Frequent hypermethylation of RASSF1A and TSLC1, and high viral load of Epstein-Barr Virus DNA in nasopharyngeal carcinoma and matched tumor-adjacent tissues.SOX10, a novel HMG-box-containing tumor suppressor, inhibits growth and metastasis of digestive cancers by suppressing the Wnt/β-catenin pathway.Oncogenic induction of cellular high CpG methylation by Epstein-Barr virus in malignant epithelial cellsStealth technology: how Epstein-Barr virus utilizes DNA methylation to cloak itself from immune detection.Methylation status of the Epstein-Barr virus major latent promoter C in iatrogenic B cell lymphoproliferative disease. Application of PCR-based analysis.Epigenetic silencing of a Ca(2+)-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers.Protocadherin PCDH10, involved in tumor progression, is a frequent and early target of promoter hypermethylation in cervical cancer.A single nucleotide polymorphism in the Epstein-Barr virus genome is strongly associated with a high risk of nasopharyngeal carcinomaEpstein-Barr virus (EBV) and its associated human cancers--genetics, epigenetics, pathobiology and novel therapeutics.Dapper homolog 1 is a novel tumor suppressor in gastric cancer through inhibiting the nuclear factor-κB signaling pathway.Epigenetic silencing of the 3p22 tumor suppressor DLEC1 by promoter CpG methylation in non-Hodgkin and Hodgkin lymphomas.Paired box 5 is a frequently methylated lung cancer tumour suppressor gene interfering β-catenin signalling and GADD45G expressionDACT1, an antagonist to Wnt/β-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer.DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancersThe epigenetic modifier CHD5 functions as a novel tumor suppressor for renal cell carcinoma and is predominantly inactivated by promoter CpG methylation.Epigenomic analysis of lung adenocarcinoma reveals novel DNA methylation patterns associated with smoking.Aberrant promoter CpG methylation and its translational applications in breast cancer.Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers.Protocadherin 17 functions as a tumor suppressor suppressing Wnt/β-catenin signaling and cell metastasis and is frequently methylated in breast cancer.DLC1-dependent parathyroid hormone-like hormone inhibition suppresses breast cancer bone metastasis.DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells.DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.Down-regulation of ATM protein in HRS cells of nodular sclerosis Hodgkin's lymphoma in children occurs in the absence of ATM gene inactivation.Zinc-finger protein 545 is a novel tumour suppressor that acts by inhibiting ribosomal RNA transcription in gastric cancer.BCLB, methylated in hepatocellular carcinoma, is a starvation stress sensor that induces apoptosis and autophagy through the AMPK-mTOR signaling cascade.DLEC1, a 3p tumor suppressor, represses NF-κB signaling and is methylated in prostate cancer.Receptor-type tyrosine-protein phosphatase κ directly targets STAT3 activation for tumor suppression in nasal NK/T-cell lymphoma.
P50
Q24293304-79EF7801-DD33-4082-9E3F-52AB50569833Q24537608-49413297-8E13-48BE-BB68-AE927895862EQ28385864-008BBED1-1AF0-4E4C-8F51-3A4FB4116C8EQ33361612-736BDA2A-DAAF-48C1-A645-EF1B2143C117Q33836449-7F9C0E24-E2A7-4025-A80C-A2A6B44E13C5Q33842261-48F2AD8B-0C57-4708-BE08-D83908129172Q33889229-7FA6600F-8B40-4F48-A89A-603499875D1FQ34075626-4A9B6CDE-9A5C-456E-BEAD-3AFDB874EA7CQ34141646-A3FDCA27-9462-4941-82C4-56045682AC2DQ34318060-7076AEAB-1E51-4C85-B686-CC2D5073FF6AQ34434311-98D7943F-A575-49F8-AB52-C67E8D422653Q34549691-4B094AD5-F53C-4609-8FDB-AFE63C922011Q34612189-1F7FE92C-86FE-496C-A592-83F465329408Q34769720-8BBC6239-AF06-47F5-A5D8-9B0CD3C96BDAQ34786506-A34A2A53-A008-4F26-9562-5C96824A70C5Q35020438-2224EEC3-4114-48DB-B0D9-14689E74C51EQ35571278-FBEEB953-E4A2-4D5D-AA85-9CF270C48ABEQ35787708-FC3ABB13-46CF-4659-9E83-6BEFD2F2E761Q35927921-F26A2510-9736-47C0-BB91-B9756561F812Q36197642-EEB77241-A916-4B99-8576-3FF2872E38E4Q36424931-639C84D8-B186-43DE-A5D4-2C8D6EE9C9DDQ36486650-FEEB345C-6D04-410C-9D8C-3FAFB9C6D852Q36498313-8B08D5EB-169A-4661-B4C2-B9CBBD8B668DQ36517724-A5522646-68FD-4D26-8D7B-53B9CEC77E34Q36797506-F9F52035-EC27-4B6D-88F4-C40AA5AD04DDQ36903109-514E91F0-9233-4AA3-9C92-7F7BD8E5311BQ37123409-661D5988-21F4-4198-80ED-529F046169F4Q37225359-F62177BA-0853-4EB0-A7C8-C191FD6AB95DQ37281397-C19337AE-065E-40FB-9A5D-7CA8A4023522Q37354053-8A73B836-7449-42D1-BFBA-F1059C859ABBQ37562716-79A199D9-BB54-4FC6-ACCD-FBAFC232B817Q37588356-51DEAAEC-928A-495F-BB4B-81261CEB3D1BQ37679939-F29176BC-667B-464E-91A7-B2A4FA80CE72Q37684412-044D53A3-646F-412F-A1A2-648AC2DCE0D9Q38296215-6396E460-F057-4BCB-BDA2-974D177814AAQ38298223-FCF368CE-197D-438F-801D-57330C205532Q38325404-D6AC9666-269B-4DAF-844F-F055D7FAC9C3Q38713903-A2E19A52-ACE3-4D17-AE77-207CB9BA9E48Q38913306-29CAB28C-3CE8-46F1-A08B-EC8F895AAA40Q38917500-967E461B-313C-419A-8B21-8350F20E1FBF
P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0001-5383-4808
@en
name
Qian Tao
@ast
Qian Tao
@en
Qian Tao
@es
Qian Tao
@nl
type
label
Qian Tao
@ast
Qian Tao
@en
Qian Tao
@es
Qian Tao
@nl
prefLabel
Qian Tao
@ast
Qian Tao
@en
Qian Tao
@es
Qian Tao
@nl
P106
P31
P496
0000-0001-5383-4808