Pharmacokinetic Studies of Baclofen Are Not Sufficient to Establish an Optimized Dosage for Management of Alcohol Disorder

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Pharmacokinetic Studies of Baclofen Are Not Sufficient to Establish an Optimized Dosage for Management of Alcohol Disorder

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scientific article published on 05 October 2018

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wetenschappelijk artikel

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наукова стаття, опублікована у 2018

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Pharmacokinetic Studies of Bac ...... Management of Alcohol Disorder

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Pharmacokinetic Studies of Bac ...... Management of Alcohol Disorder

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Pharmacokinetic Studies of Bac ...... Management of Alcohol Disorder

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Pharmacokinetic Studies of Bac ...... Management of Alcohol Disorder

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Pharmacokinetic Studies of Bac ...... Management of Alcohol Disorder

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Pharmacokinetic Studies of Bac ...... Management of Alcohol Disorder

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P1476

Pharmacokinetic Studies of Bac ...... Management of Alcohol Disorder

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P2093

Nicolas Franchitto

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P2860

The organic anion transporter (OAT) family: a systems biology perspective

Lipophilicities of baclofen ester prodrugs correlate with affinities to the ATP-dependent efflux pump P-glycoprotein: relevance for their permeation across the blood-brain barrier?

The bioequivalence study of baclofen and lioresal tablets using capillary electrophoresis.

Stereoselective transport of baclofen across the blood-brain barrier in rats as determined by the unit impulse response methodology.

High variability in the exposure of baclofen in alcohol-dependent patients.

The chemistry and kinetics of Lioresal.

Study on brain interstitial fluid distribution and blood-brain barrier transport of baclofen in rats by microdialysis.

Changes in plasma protein binding have little clinical relevance.

Plasma and urinary excretion kinetics of oral baclofen in healthy subjects.

High-dose baclofen for the treatment of alcohol dependence (BACLAD study): a randomized, placebo-controlled trial.

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485

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scholarly article

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10.3389/FPSYT.2018.00485

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P407

English

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P50

Benjamin Rolland

Nicolas Simon

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2018-10-05T00:00:00Z

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P698

30349489

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P932

6186984

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