Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population
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Genetic factors affecting statin concentrations and subsequent myopathy: a HuGENet systematic reviewA mechanistic, model-based approach to safety assessment in clinical developmentPharmacogenomic characterization of gemcitabine response--a framework for data integration to enable personalized medicine.Application of a Physiologically Based Pharmacokinetic Model to Predict OATP1B1-Related Variability in Pharmacodynamics of Rosuvastatin.Frequencies of two functionally significant SNPs and their haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in six ethnic groups of Pakistani population.Mechanisms and assessment of statin-related muscular adverse effects.Statin pharmacogenomics: opportunities to improve patient outcomes and healthcare costs with genetic testingImpact of OATP transporters on pharmacokinetics.The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy.SLCO1B1 Variants and Angiotensin Converting Enzyme Inhibitor (Enalapril)-Induced Cough: a Pharmacogenetic Study.No significant effect of SLCO1B1 polymorphism on the pharmacokinetics of rosiglitazone and pioglitazone.Frequencies of single-nucleotide polymorphisms and haplotypes of the SLCO1B1 gene in selected populations of the western balkans.Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humans.Pharmacogenetics of glucose-lowering drug treatment: a systematic review.Role of OATP transporters in the disposition of drugs.Polymorphic variants of SLCO1B1 in neonatal hyperbilirubinemia in China.The effect of SLCO1B1 polymorphism on repaglinide pharmacokinetics persists over a wide dose range.No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin.Impact of SLCO1B1 (OATP1B1) and ABCG2 (BCRP) genetic polymorphisms and inhibition on LDL-C lowering and myopathy of statins.Towards safer and more predictable drug treatment--reflections from studies of the First BCPT Prize awardee.Ethnic variability in the plasma exposures of OATP1B1 substrates such as HMG-CoA reductase inhibitors: a kinetic consideration of its mechanism.Explaining Ethnic Variability of Transporter Substrate Pharmacokinetics in Healthy Asian and Caucasian Subjects with Allele Frequencies of OATP1B1 and BCRP: A Mechanistic Modeling Analysis.Impact of Transporter Polymorphisms on Drug Development: Is It Clinically Significant?Global analysis of genetic variation in SLCO1B1.Frequency distribution of polymorphisms of CYP2C19, CYP2C9, VKORC1 and SLCO1B1 genes in the Yakut populationRole of vitamin D pathway gene polymorphisms on rifampicin plasma and intracellular pharmacokinetics.Genotyping of OATP2 Variants in a Group of Malaysian Neonates Using High-Resolution Melting AnalysisPharmGKB very important pharmacogene: SLCO1B1.Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin.Quantitative population pharmacokinetic analysis of pravastatin using an enterohepatic circulation model combined with pharmacogenomic Information on SLCO1B1 and ABCC2 polymorphisms.Frequency of the SLCO1B1 388A>G and the 521T>C polymorphism in Tanzania genotyped by a new LightCycler®-based method.ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin.Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism.ABCB1 haplotypes differentially affect the pharmacokinetics of the acid and lactone forms of simvastatin and atorvastatin.Different effects of SLCO1B1 polymorphism on the pharmacokinetics and pharmacodynamics of repaglinide and nateglinide.Common variants in glucuronidation enzymes and membrane transporters as potential risk factors for colorectal cancer: a case control study.Genetic and Clinical Factors Are Associated With Statin-Related Myotoxicity of Moderate Severity: A Case-Control Study.No impact of SLCO1B1 521T>C, 388A>G and 411G>A polymorphisms on response to statin therapy in the Greek population.Lack of association between SLCO1B1 polymorphism and the lipid-lowering effects of atorvastatin and simvastatin in Chinese individuals.Organic anion transporting polypeptide-1B1 haplotypes in Chinese patients
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Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population
description
article
@en
im April 2006 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована у квітні 2006
@uk
name
Frequencies of single nucleoti ...... 1 gene in a Finnish population
@en
Frequencies of single nucleoti ...... 1 gene in a Finnish population
@nl
type
label
Frequencies of single nucleoti ...... 1 gene in a Finnish population
@en
Frequencies of single nucleoti ...... 1 gene in a Finnish population
@nl
prefLabel
Frequencies of single nucleoti ...... 1 gene in a Finnish population
@en
Frequencies of single nucleoti ...... 1 gene in a Finnish population
@nl
P50
P1476
Frequencies of single nucleoti ...... 1 gene in a Finnish population
@en
P2093
Marja K. Pasanen
P2888
P304
P356
10.1007/S00228-006-0123-1
P577
2006-04-21T00:00:00Z