Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells
about
Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activationFgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.Transcriptional regulators of the trophoblast lineage in mammals with hemochorial placentation.The progenitor state is maintained by lysine-specific demethylase 1-mediated epigenetic plasticity during Drosophila follicle cell development.Adaptive mechanisms controlling uterine spiral artery remodeling during the establishment of pregnancy.KDM1A/LSD1 regulates the differentiation and maintenance of spermatogonia in mice.Maternal DNA Methylation Regulates Early Trophoblast DevelopmentMaternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally.Epigenetic regulation of LSD1 during mammary carcinogenesis.Lsd1 prevents age-programed loss of beige adipocytes.Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.A Resource for the Transcriptional Signature of Bona Fide Trophoblast Stem Cells and Analysis of Their Embryonic Persistence.Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4.LSD1 protects against hippocampal and cortical neurodegeneration.Mapping the chromatin landscape and Blimp1 transcriptional targets that regulate trophoblast differentiation.Second German-Catalan workshop on epigenetics & cancer.Neuroepigenetic mechanisms in disease.LSD1 promotes oxidative metabolism of white adipose tissueFAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1.Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells.AMPK improves gut epithelial differentiation and barrier function via regulating Cdx2 expression.
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Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells
description
article publié dans Nature Communications
@fr
im Januar 2014 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Nature Communications
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2014
@uk
name
Lysine-specific demethylase 1 ...... tion of trophoblast stem cells
@en
Lysine-specific demethylase 1 ...... tion of trophoblast stem cells
@nl
type
label
Lysine-specific demethylase 1 ...... tion of trophoblast stem cells
@en
Lysine-specific demethylase 1 ...... tion of trophoblast stem cells
@nl
prefLabel
Lysine-specific demethylase 1 ...... tion of trophoblast stem cells
@en
Lysine-specific demethylase 1 ...... tion of trophoblast stem cells
@nl
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P356
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Lysine-specific demethylase 1 ...... tion of trophoblast stem cells
@en
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Anett Jandausch
Cordula Jilg
Dongmei Zhu
Eric Metzger
Markus Moser
Mihael Pavlovic
Petra Galgoczy
Roland Schüle
Sebastian J. Arnold
Stefanie Hölz
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P2888
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10.1038/NCOMMS4174
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P577
2014-01-22T00:00:00Z