about
Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypesProlonged and substantial discordance in prevalence of raltegravir-resistant HIV-1 in plasma versus PBMC samples revealed by 454 "deep" sequencingReliable genotypic tropism tests for the major HIV-1 subtypesLimited evolution of inferred HIV-1 tropism while viremia is undetectable during standard HAART therapyPrevalence and virologic consequences of transmitted HIV-1 drug resistance in UgandaNon-R5-tropic HIV-1 in subtype A1 and D infections were associated with lower pretherapy CD4+ cell count but not with PI/(N)NRTI therapy outcomes in Mbarara, UgandaPrevalence and clinical impacts of HIV-1 intersubtype recombinants in Uganda revealed by a near-full-genome population and deep sequencing approaches.Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression.Potential for immune-driven viral polymorphisms to compromise antiretroviral-based preexposure prophylaxis for prevention of HIV-1 infection.Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells.In vitro functional assessment of natural HIV-1 group M Vpu sequences using a universal priming approach.Diversity of HIV-1 reservoirs in CD4+ T-cell subpopulations.Should abacavir be a first-line alternative for adults with HIV in sub-Saharan Africa?Comparison of population and 454 "deep" sequence analysis for HIV type 1 tropism versus the original trofile assay in non-B subtypes.Highly frequent HIV-1 minority resistant variants at baseline of the ANRS 139 TRIO trial had a limited impact on virological response.Theoretical and experimental assessment of degenerate primer tagging in ultra-deep applications of next-generation sequencing.Convergence of Ser/Thr and two-component signaling to coordinate expression of the dormancy regulon in Mycobacterium tuberculosisExtensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study.Dolutegravir reshapes the genetic diversity of HIV-1 reservoirs.Effect of analytical treatment interruption and reinitiation of antiretroviral therapy on HIV reservoirs and immunologic parameters in infected individuals.HLA-C downregulation by HIV-1 adapts to host HLA genotypeHIV-1 DNA sequence diversity and evolution during acute subtype C infectionHIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollersIntact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapyTissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection
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description
researcher, ORCID id # 0000-0002-9412-886X
@en
wetenschapper
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name
Guinevere Q Lee
@ast
Guinevere Q Lee
@en
Guinevere Q Lee
@es
Guinevere Q Lee
@nl
type
label
Guinevere Q Lee
@ast
Guinevere Q Lee
@en
Guinevere Q Lee
@es
Guinevere Q Lee
@nl
prefLabel
Guinevere Q Lee
@ast
Guinevere Q Lee
@en
Guinevere Q Lee
@es
Guinevere Q Lee
@nl
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0000-0002-9412-886X