Functional Characterization of the Novel APC N1026S Variant Associated With Attenuated Familial Adenomatous Polyposis
about
Genotype to phenotype: analyzing the effects of inherited mutations in colorectal cancer families.Genetic predisposition to colorectal cancer: where we stand and future perspectivesPolymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma riskIsolation and propagation of a human CD133(-) colon tumor-derived cell line with tumorigenic and angiogenic properties.PRL-3 is essentially overexpressed in primary colorectal tumours and associates with tumour aggressiveness.Analysis of rare APC variants at the mRNA level: six pathogenic mutations and literature review.Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients.Allele-specific expression of APC in adenomatous polyposis families.Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype.Oncogenic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas
P2860
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P2860
Functional Characterization of the Novel APC N1026S Variant Associated With Attenuated Familial Adenomatous Polyposis
description
im Januar 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 10 October 2007
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2008
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name
Functional Characterization of ...... Familial Adenomatous Polyposis
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Functional Characterization of ...... Familial Adenomatous Polyposis
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type
label
Functional Characterization of ...... Familial Adenomatous Polyposis
@en
Functional Characterization of ...... Familial Adenomatous Polyposis
@nl
prefLabel
Functional Characterization of ...... Familial Adenomatous Polyposis
@en
Functional Characterization of ...... Familial Adenomatous Polyposis
@nl
P2093
P50
P1433
P1476
Functional characterization of ...... familial adenomatous polyposis
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P2093
Ana Domínguez
Antonio Pineda-Lucena
Antònia Obrador-Hevia
Asunción Torres
Maria Jesús Pujol
Oriol Bachs
Sara González
P356
10.1053/J.GASTRO.2007.10.009
P407
P577
2007-10-10T00:00:00Z