Cloning and characterization of novel tumor-targeting immunocytokines based on murine IL7
about
Immunocytokines and bispecific antibodies: two complementary strategies for the selective activation of immune cells at the tumor siteImmunoglobulin Fc Heterodimer Platform Technology: From Design to Applications in Therapeutic Antibodies and ProteinsA critical evaluation of the tumor-targeting properties of bispecific antibodies based on quantitative biodistribution data.The antibody-based targeted delivery of TNF in combination with doxorubicin eradicates sarcomas in mice and confers protective immunity.A human monoclonal antibody specific to placental alkaline phosphatase, a marker of ovarian cancer.Murine analogues of etanercept and of F8-IL10 inhibit the progression of collagen-induced arthritis in the mouse.Latent cytokines for targeted therapy of inflammatory disorders.Non-internalizing antibody-drug conjugates display potent anti-cancer activity upon proteolytic release of monomethyl auristatin E in the subendothelial extracellular matrix.Antibody Format and Drug Release Rate Determine the Therapeutic Activity of Noninternalizing Antibody-Drug Conjugates.The antibody-mediated targeted delivery of interleukin-13 to syngeneic murine tumors mediates a potent anticancer activity.Tumor-targeting properties of novel immunocytokines based on murine IL1β and IL6.Evaluation of antibody-chemokine fusion proteins for tumor-targeting applications.Tumor rim cells: From resistance to vascular targeting agents to complete tumor ablation.The targeted delivery of IL17 to the mouse tumor neo-vasculature enhances angiogenesis but does not reduce tumor growth rate.Evolution of the magic bullet: Single chain antibody fragments for the targeted delivery of immunomodulatory proteins.Novel antibody-cytokine fusion proteins featuring granulocyte-colony stimulating factor, interleukin-3 and interleukin-4 as payloads.The antibody-based targeted delivery of interleukin-4 and 12 to the tumor neovasculature eradicates tumors in three mouse models of cancer.Potency-matched Dual Cytokine-Antibody Fusion Proteins for Cancer Therapy.Alternatively Spliced EDA Domain of Fibronectin Is a Target for Pharmacodelivery Applications in Inflammatory Bowel Disease.A novel dual-cytokine-antibody fusion protein for the treatment of CD38-positive malignanciesEmerging classes of armed antibody therapeutics against cancer
P2860
Q28066935-119CE03B-D270-4A7E-A541-2F844739553BQ28072319-9242630E-0560-41FB-8927-AB6893A6D9F8Q30564779-9C19BA9C-5D45-465F-9A6E-4D3FBA65B925Q37185752-35D05367-C97D-4E95-A785-637A629CC9F0Q37593714-30D6FFAC-F26F-4EAC-8915-CE2E57A276A3Q37690616-7BCE927F-BBC7-40E1-BC24-0DC4BB9E3511Q38167818-B860B5BC-6FDB-49BA-BF56-12B66416F438Q38726647-002EC474-84FF-416A-822B-586BBE8E0824Q38842103-C2C02FB0-72A7-40E5-B0C2-F23113B5A4F3Q38905573-7078442A-BB84-4988-A416-A9AAFB6AF721Q38998638-52DCAF92-9ACE-456C-8758-19132CD937DCQ39185087-58D54451-5076-421E-89F0-C50654F8BFCEQ39205186-39F4C710-B4E4-4E4F-AC50-0C59CFA95646Q39448373-744FC45B-D284-4A20-9866-45C471CF7F22Q47277628-6CFF869C-F40D-4D94-8AD8-F47664C4035DQ50039410-70C22149-C618-4973-9B9F-CE739F079654Q50864449-EBAAF678-D6CA-4343-9D88-0EA29CD678D9Q50885364-BF5252BE-5DEB-422C-9387-0C55E4966B8EQ53499740-BECE1CB9-8324-408E-AF4A-4537E917488EQ57201583-76534556-BF3A-4E85-A2DD-02A4FD25E568Q57911948-C3B245AF-0A35-4075-926F-51C82EED6CA0
P2860
Cloning and characterization of novel tumor-targeting immunocytokines based on murine IL7
description
im Juni 2011 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в червні 2011
@uk
name
Cloning and characterization of novel tumor-targeting immunocytokines based on murine IL7
@en
Cloning and characterization of novel tumor-targeting immunocytokines based on murine IL7
@nl
type
label
Cloning and characterization of novel tumor-targeting immunocytokines based on murine IL7
@en
Cloning and characterization of novel tumor-targeting immunocytokines based on murine IL7
@nl
prefLabel
Cloning and characterization of novel tumor-targeting immunocytokines based on murine IL7
@en
Cloning and characterization of novel tumor-targeting immunocytokines based on murine IL7
@nl
P2093
P1476
Cloning and characterization of novel tumor-targeting immunocytokines based on murine IL7
@en
P2093
Alessandra Villa
Janine Woytschak
Katharina Frey
Nadine Pasche
Sarah Wulhfard
P356
10.1016/J.JBIOTEC.2011.04.003
P50
P577
2011-06-01T00:00:00Z