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Find the weakest link. A comparison between demographic, genetic and demo-genetic metapopulation extinction timesGood genes sexual selection in natureDeleterious alleles and differential viability in progeny of natural hemiclonal frogs.A general multivariate extension of Fisher's geometrical model and the distribution of mutation fitness effects across species.Factors affecting the genetic load in Drosophila: synergistic epistasis and correlations among fitness components.Comparative evolutionary genetics of spontaneous mutations affecting fitness in rhabditid nematodesAlbinism and phenotype of barn swallows (Hirundo rustica) from Chernobyl.Reduced selective constraint in endosymbionts: elevation in radical amino acid replacements occurs genome-wide.Fixation of new alleles and the extinction of small populations: drift load, beneficial alleles, and sexual selection.Linkage limits the power of natural selection in Drosophila.Toward a realistic model of mutations affecting fitness.Fitness recovery and compensatory evolution in natural mutant lines of C. elegans.High relatedness is necessary and sufficient to maintain multicellularity in Dictyostelium.Perspective: Evolution and detection of genetic robustness.Baubles, bangles, and biotypes: a critical review of the use and abuse of the biotype concept.Metapopulation extinction caused by mutation accumulation.Evolutionary invasion and escape in the presence of deleterious mutations.Male-biased transmission of deleterious mutations to the progeny in Arabidopsis thaliana.Epistasis correlates to genomic complexity.Causes of natural variation in fitness: evidence from studies of Drosophila populations.The efficiency of close inbreeding to reduce genetic adaptation to captivity.Spontaneous deleterious mutation in Arabidopsis thaliana.The dominance effect of the adaptive transposable element insertion Bari-Jheh depends on the genetic backgroundComplete genetic linkage can subvert natural selection.Inbreeding depression and drift load in small populations at demographic disequilibrium.Power provides protection: Genetic robustness in yeast depends on the capacity to generate energy.The effect of spontaneous mutations on competitive abilityA genome-wide view of the spectrum of spontaneous mutations in yeast.Evolutionary diversification of the multimeric states of proteins.Mutation load under additive fitness effects.Analysis and implications of mutational variation.Molecular population genomics: a short history.Widespread fitness alignment in the legume-rhizobium symbiosis.The effects of natural variation in background radioactivity on humans, animals and other organisms.The repeatability of genome-wide mutation rate and spectrum estimatesIn Genes We Trust: Germline Engineering, Eugenics, and the Future of the Human Genome.The fitness effects of a point mutation in Escherichia coli change with founding population density.Spontaneous mutation accumulation in multiple strains of the green alga, Chlamydomonas reinhardtii.Spatial heterogeneity in the strength of selection against deleterious alleles and the mutation load.Cross-resistance, the stability of acetamiprid resistance and its effect on the biological parameters of cotton mealybug, Phenacoccus solenopsis (Homoptera: Pseudococcidae), in Pakistan.
P2860
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P2860
description
article
@en
im Juni 1999 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в червні 1999
@uk
name
Perspective: Spontaneous Deleterious Mutation
@en
Perspective: Spontaneous Deleterious Mutation
@nl
type
label
Perspective: Spontaneous Deleterious Mutation
@en
Perspective: Spontaneous Deleterious Mutation
@nl
prefLabel
Perspective: Spontaneous Deleterious Mutation
@en
Perspective: Spontaneous Deleterious Mutation
@nl
P2093
P356
P1433
P1476
Perspective: Spontaneous Deleterious Mutation
@en
P2093
Jeff Blanchard
John Willis
Larissa Vassilieva
Michael Lynch
Stewart Schultz
Travis Kibota
P356
10.2307/2640707
P50
P577
1999-06-01T00:00:00Z