Dissecting Sites Important for Complement Regulatory Activity in Membrane Cofactor Protein (MCP; CD46) - Wikidata - wikimedia - TriplyDB

Dissecting Sites Important for Complement Regulatory Activity in Membrane Cofactor Protein (MCP; CD46)

Dissecting Sites Important for Complement Regulatory Activity in Membrane Cofactor Protein (MCP; CD46)

http://www.wikidata.org/entity/Q57936817

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Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype Structure of complement fragment C3b-factor H and implications for host protection by complement regulators Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (aHUS), fatal Stx-HUS, C3 glomerulonephritis, and the HELLP syndrome Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome Function of bovine CD46 as a cellular receptor for bovine viral diarrhea virus is determined by complement control protein 1 West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H Complement and its role in protection and pathogenesis of flavivirus infections Structure of the Extracellular Portion of CD46 Provides Insights into Its Interactions with Complement Proteins and Pathogens Human Herpesvirus 6 and Measles Virus Employ Distinct CD46 Domains for Receptor Function Complement regulator CD46: genetic variants and disease associations Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort CD46-induced immunomodulatory CD4+ T cells express the adhesion molecule and chemokine receptor pattern of intestinal T cells Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome.Modeling how CD46 deficiency predisposes to atypical hemolytic uremic syndrome Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome Manifestation of atypical hemolytic uremic syndrome caused by novel mutations in MCP.Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome.Targeted and restricted complement activation on acrosome-reacted spermatozoa.Olfactory nerve--a novel invasion route of Neisseria meningitidis to reach the meninges.CD46-induced human Treg enhance B-cell responses.Smallpox inhibitor of complement enzymes (SPICE): dissecting functional sites and abrogating activity Variola virus immune evasion design: expression of a highly efficient inhibitor of human complement.Ectromelia virus inhibitor of complement enzymes protects intracellular mature virus and infected cells from mouse complement.Regulator of complement activation (RCA) group 2 gene cluster in zebrafish: identification, expression, and evolution.Whole-exome sequencing identifies rare, functional CFH variants in families with macular degeneration.Complement regulatory protein CD46 protects against choroidal neovascularization in mice.CD46 engagement on human CD4+ T cells produces T regulatory type 1-like regulation of antimycobacterial T cell responses Complement System Part I - Molecular Mechanisms of Activation and Regulation.Immunophysical properties and prediction of activities for vaccinia virus complement control protein and smallpox inhibitor of complement enzymes using molecular dynamics and electrostatics.Structure of vaccinia complement protein in complex with heparin and potential implications for complement regulation.Genetic analysis of membrane cofactor protein (CD46) of the complement system in women with and without preeclamptic pregnancies.A novel role for CD46 in wound repair Mutational analysis of Kaposica reveals that bridging of MG2 and CUB domains of target protein is crucial for the cofactor activity of RCA proteins.Complement Dysregulation and Disease: Insights from Contemporary Genetics.Down-regulation of CD46 by piliated Neisseria gonorrhoeae.Identification of hot spots in the variola virus complement inhibitor (SPICE) for human complement regulation.Dissection of functional sites in herpesvirus saimiri complement control protein homolog.Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode.CD46 is a cellular receptor for bovine viral diarrhea virus.

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Dissecting Sites Important for Complement Regulatory Activity in Membrane Cofactor Protein (MCP; CD46)

http://www.wikidata.org/entity/Q57936817

description

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

im August 2000 veröffentlichter wissenschaftlicher Artikel

@de

scientific article published in Journal of Biological Chemistry

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в серпні 2000

@uk

name

Dissecting Sites Important for ...... e Cofactor Protein (MCP; CD46)

@en

Dissecting Sites Important for ...... y in Membrane Cofactor Protein

@nl

type

label

Dissecting Sites Important for ...... e Cofactor Protein (MCP; CD46)

@en

Dissecting Sites Important for ...... y in Membrane Cofactor Protein

@nl

prefLabel

Dissecting Sites Important for ...... e Cofactor Protein (MCP; CD46)

@en

Dissecting Sites Important for ...... y in Membrane Cofactor Protein

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Journal of Biological Chemistry

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Dissecting Sites Important for ...... e Cofactor Protein (MCP; CD46)

@en

P2093

John P. Atkinson

http://www.w3.org/2001/XMLSchema#string

M. Kathryn Liszewski

http://www.w3.org/2001/XMLSchema#string

Marilyn Leung

http://www.w3.org/2001/XMLSchema#string

Paul N. Barlow

http://www.w3.org/2001/XMLSchema#string

V. Bala Subramanian

http://www.w3.org/2001/XMLSchema#string

Wenying Cui

http://www.w3.org/2001/XMLSchema#string

P2860

Decay accelerating activity of complement receptor type 1 (CD35). Two active sites are required for dissociating C5 convertases

The human CD46 molecule is a receptor for measles virus (Edmonston strain)

Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype

Basic local alignment search tool

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

Crystal structure of two CD46 domains reveals an extended measles virus-binding surface

Adhesion mechanism of human beta(2)-glycoprotein I to phospholipids based on its crystal structure.

Crystal structure of human β2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome

Solution structure of a pair of complement modules by nuclear magnetic resonance

NMR studies of a viral protein that mimics the regulators of complement activation

P304

37692-37701

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scholarly article

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10.1074/JBC.M004650200

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P407

P433

48

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275

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Marianne Manchester

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2000-08-25T00:00:00Z

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P698

10960475

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