Srs2 enables checkpoint recovery by promoting disassembly of DNA damage foci from chromatin
about
Genetic instability in budding and fission yeast-sources and mechanismsRad52 sumoylation prevents the toxicity of unproductive Rad51 filaments independently of the anti-recombinase Srs2Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance.Rad51 ATP binding but not hydrolysis is required to recruit Rad10 in synthesis-dependent strand annealing sites in S. cerevisiae.Functions of Fun30 chromatin remodeler in regulating cellular resistance to genotoxic stressDNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants.SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination.Unloading of homologous recombination factors is required for restoring double-stranded DNA at damage repair loci.Constructing module maps for integrated analysis of heterogeneous biological networks.Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.Delineation of the role of chromatin assembly and the Rtt101Mms1 E3 ubiquitin ligase in DNA damage checkpoint recovery in budding yeast.The Saccharomyces cerevisiae chromatin remodeler Fun30 regulates DNA end resection and checkpoint deactivation.Replication checkpoint: tuning and coordination of replication forks in s phase.Break-induced replication promotes formation of lethal joint molecules dissolved by Srs2.Perinuclear tethers license telomeric DSBs for a broad kinesin- and NPC-dependent DNA repair process.A functional autophagy pathway is required for rapamycin-induced degradation of the Sgs1 helicase in Saccharomyces cerevisiae.
P2860
Q28264035-1D49FEBB-8291-488D-B13E-BC2A43057065Q28534315-9AFDBF60-3874-437F-B2B8-AC94FB43AA41Q33649550-CF1FDDD9-D4D7-491A-AE96-D0B9DD9A8CFDQ34385513-B21E9F53-5816-469E-9E89-7BD4DE6A9C9DQ35586091-3900745B-9029-42FC-850B-B0F3C4C01F6DQ37056627-D79D214C-80DA-4057-80E1-9290AEB0E7B2Q37313069-5E780DF8-1737-4936-83BE-9FF993445600Q37588770-A73432E5-1D79-4794-BF90-B9813C4654CDQ38736165-418BA6EA-22AB-4C45-932A-F98C4ADA3FB1Q39052177-9E808F27-BE58-426B-9AA4-4571459BC219Q41153815-EF7E9FF3-5E5A-4F01-802B-3CC9C26AF4E8Q41581707-84F3D78B-FBF8-4653-BACC-B90D9FA1DF7CQ41789965-08CDD1A3-BC84-4010-978B-7F7DB6062414Q47112510-B42FDACD-D1CE-4B1B-9892-B91C79FC13DFQ48154912-7E1DF2C0-4FDC-42F2-AEF0-36FE72D5E59EQ50998148-F0CE196B-D37E-4332-94A7-D7D4187690D6
P2860
Srs2 enables checkpoint recovery by promoting disassembly of DNA damage foci from chromatin
description
im Dezember 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 05 October 2011
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в грудні 2011
@uk
name
Srs2 enables checkpoint recove ...... DNA damage foci from chromatin
@en
Srs2 enables checkpoint recove ...... DNA damage foci from chromatin
@nl
type
label
Srs2 enables checkpoint recove ...... DNA damage foci from chromatin
@en
Srs2 enables checkpoint recove ...... DNA damage foci from chromatin
@nl
prefLabel
Srs2 enables checkpoint recove ...... DNA damage foci from chromatin
@en
Srs2 enables checkpoint recove ...... DNA damage foci from chromatin
@nl
P1433
P1476
Srs2 enables checkpoint recove ...... DNA damage foci from chromatin
@en
P2093
ManTek Yeung
P304
P356
10.1016/J.DNAREP.2011.09.005
P577
2011-10-05T00:00:00Z