Chromosome 14q32 translocations involving the immunoglobulin heavy chain locus in chronic lymphocytic leukaemia identify a disease subset with poor prognosis
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The clinical implications of gene mutations in chronic lymphocytic leukaemiaChromosomal translocations and karyotype complexity in chronic lymphocytic leukemia: a systematic reappraisal of classic cytogenetic data.An extensive molecular cytogenetic characterization in high-risk chronic lymphocytic leukemia identifies karyotype aberrations and TP53 disruption as predictors of outcome and chemorefractorinessGenetic abnormalities in chronic lymphocytic leukemia: where we are and where we goModern treatment in chronic lymphocytic leukemia: impact on survival and efficacy in high-risk subgroupsMicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia.Recurrent amplification at 7q21.2 Targets CDK6 gene in primary myxofibrosarcomas and identifies CDK6 overexpression as an independent adverse prognosticator.Specific chromosomal IG translocations have different prognoses in chronic lymphocytic leukemia.Immunoglobulin gene translocations in chronic lymphocytic leukemia: A report of 35 patients and review of the literature.Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6.A high number of losses in 13q14 chromosome band is associated with a worse outcome and biological differences in patients with B-cell chronic lymphoid leukemia.Extensive next-generation sequencing analysis in chronic lymphocytic leukemia at diagnosis: clinical and biological correlationst(14;18)(q32;q21) in chronic lymphocytic leukemia patients: Report of two cases and a literature review.Clinicobiologic importance of cytogenetic lesions in chronic lymphocytic leukemia.Controversial fluorescence in situ hybridization cytogenetic abnormalities in chronic lymphocytic leukaemia: new insights from a large cohort.Cytogenetic and flow cytometry evaluation of Richter syndrome reveals MYC, CDKN2A, IGH alterations with loss of CD52, CD62L and increase of CD71 antigen expression as the most frequent recurrent abnormalities.Chronic Lymphocytic Leukemia with t(14;18)(q32;q21) As a Sole Cytogenetic Abnormality.Genetic lesions in chronic lymphocytic leukemia: what's ready for prime time use?Concurrent rearrangements of BCL2, BCL3, and BCL11A genes in atypical chronic lymphocytic leukemia.Immunoglobulin heavy-chain fluorescence in situ hybridization-chromogenic in situ hybridization DNA probe split signal in the clonality assessment of lymphoproliferative processes on cytological samples.Influence of clone and deletion size on outcome in chronic lymphocytic leukemia patients with an isolated deletion 13q in a population-based analysis in British Columbia, Canada.Impact of Fluorescent In Situ Hybridization Aberrations and CLLU1 Expression on the Prognosis of Chronic Lymphocytic Leukemia: Presentation of 156 Patients from Turkey.Chromosome aberrations detected by conventional karyotyping using novel mitogens in chronic lymphocytic leukemia: Clinical and biologic correlations.Proliferation centers in chronic lymphocytic leukemia: correlation with cytogenetic and clinicobiological features in consecutive patients analyzed on tissue microarrays.In non-follicular lymphoproliferative disorders, IGH/BCL2-fusion is not restricted to chronic lymphocytic leukaemia.Different distribution of NOTCH1 mutations in chronic lymphocytic leukemia with isolated trisomy 12 or associated with other chromosomal alterations.Clonal evolution including 14q32/IGH translocations in chronic lymphocytic leukemia: analysis of clinicobiologic correlations in 105 patients.A new genetic abnormality leading to TP53 gene deletion in chronic lymphocytic leukaemia
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P2860
Chromosome 14q32 translocations involving the immunoglobulin heavy chain locus in chronic lymphocytic leukaemia identify a disease subset with poor prognosis
description
im Juni 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 28 June 2008
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в червні 2008
@uk
name
Chromosome 14q32 translocation ...... ase subset with poor prognosis
@en
Chromosome 14q32 translocation ...... ase subset with poor prognosis
@nl
type
label
Chromosome 14q32 translocation ...... ase subset with poor prognosis
@en
Chromosome 14q32 translocation ...... ase subset with poor prognosis
@nl
prefLabel
Chromosome 14q32 translocation ...... ase subset with poor prognosis
@en
Chromosome 14q32 translocation ...... ase subset with poor prognosis
@nl
P2093
P2860
P50
P1476
Chromosome 14q32 translocation ...... ase subset with poor prognosis
@en
P2093
Antonella Bardi
Antonella Russo Rossi
Antonio Cuneo
Cristiano De Angeli
Elisa Tammiso
Francesco Lauria
Giuseppe Torelli
Jesus Maria Hernandez
Maria Pia Lenoci
Patricia Martin-Jimenez
P2860
P304
P356
10.1111/J.1365-2141.2008.07227.X
P407
P50
P577
2008-06-28T00:00:00Z