Quantum Mechanical/Molecular Mechanical Study of Mechanisms of Heme Degradation by the Enzyme Heme Oxygenase: The Strategic Function of the Water Cluster

Quantum Mechanical/Molecular Mechanical Study of Mechanisms of Heme Degradation by the Enzyme Heme Oxygenase: The Strategic Function of the Water Cluster

Item
http://www.wikidata.org/entity/Q58095102
Crystallographic and Spectroscopic Insights into Heme Degradation by Mycobacterium tuberculosis MhuDCoupling of the distal hydrogen bond network to the exogenous ligand in substrate-bound, resting state human heme oxygenase.Coupling and uncoupling mechanisms in the methoxythreonine mutant of cytochrome P450cam: a quantum mechanical/molecular mechanical study.Electronic properties of the highly ruffled heme bound to the heme degrading enzyme IsdI.Dynamic ruffling distortion of the heme substrate in non-canonical heme oxygenase enzymes.The orbital ground state of the azide-substrate complex of human heme oxygenase is an indicator of distal H-bonding: implications for the enzyme mechanism.A selective stepwise heme oxygenase model system: an iron(IV)-oxo porphyrin π-cation radical leads to a verdoheme-type compound via an isoporphyrin intermediate.Novel lead structures and activation mechanisms for CO-releasing molecules (CORMs)Tight binding of heme to Staphylococcus aureus IsdG and IsdI precludes design of a competitive inhibitor.In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis.Hydrogen bond donation to the heme distal ligand of Staphylococcus aureus IsdG tunes the electronic structure.Function Coupling Mechanism of PhuS and HemO in Heme Degradation.Heme utilization by pathogenic bacteria: not all pathways lead to biliverdin.A single-site mutation (F429H) converts the enzyme CYP 2B4 into a heme oxygenase: a QM/MM study.Density functional theory studies on the conversion of hydroxyheme to iron-verdoheme in the presence of dioxygen.Iron chelators inhibit the heme-degradation reaction by HutZ from Vibrio cholerae.
P2860

Quantum Mechanical/Molecular Mechanical Study of Mechanisms of Heme Degradation by the Enzyme Heme Oxygenase: The Strategic Function of the Water Cluster

Item
http://www.wikidata.org/entity/Q58095102
description
2008 nî lūn-bûn
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2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
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2008年學術文章
@zh-hant
name
Quantum Mechanical/Molecular M ...... Function of the Water Cluster
@en
Quantum Mechanical/Molecular M ...... Function of the Water Cluster
@nl
type
label
Quantum Mechanical/Molecular M ...... Function of the Water Cluster
@en
Quantum Mechanical/Molecular M ...... Function of the Water Cluster
@nl
prefLabel
Quantum Mechanical/Molecular M ...... Function of the Water Cluster
@en
Quantum Mechanical/Molecular M ...... Function of the Water Cluster
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Quantum Mechanical/Molecular M ...... Function of the Water Cluster
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698