about
Twenty proteins containing a C-terminal SOCS box form five structural classesThe conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradationHair cell regeneration after ATOH1 gene therapy in the cochlea of profoundly deaf adult guinea pigs.Electroacoustic stimulation: now and into the futurePermanent and transient effects of locally delivered n-acetyl cysteine in a guinea pig model of cochlear implantation.Polypyrrole-coated electrodes for the delivery of charge and neurotrophins to cochlear neurons.Effects of localized neurotrophin gene expression on spiral ganglion neuron resprouting in the deafened cochleaNeurotrophic factors and neural prostheses: potential clinical applications based upon findings in the auditory system.Neurotrophin gene therapy for sustained neural preservation after deafness.Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction.Electrical stimulation causes rapid changes in electrode impedance of cell-covered electrodes.Principles of design and biological approaches for improving the selectivity of cochlear implant electrodes.Viability of long-term gene therapy in the cochlea.Treating hearing disorders with cell and gene therapy.Atoh1 gene therapy in the cochlea for hair cell regeneration.Challenges for the application of optical stimulation in the cochlea for the study and treatment of hearing loss.Optimising the incorporation and release of a neurotrophic factor using conducting polypyrrole.Resprouting and survival of guinea pig cochlear neurons in response to the administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3.A somatic cell genetic system for dissecting hemopoietic cytokine signal transduction.Tracing neurotrophin-3 diffusion and uptake in the guinea pig cochlea.Delivery of neurotrophin-3 to the cochlea using alginate beads.A single dose of neurotrophin-3 to the cochlea surrounds spiral ganglion neurons and provides trophic support.Relations between cochlear histopathology and hearing loss in experimental cochlear implantation.Factors influencing the efficacy of round window dexamethasone protection of residual hearing post-cochlear implant surgery.Promoting neurite outgrowth from spiral ganglion neuron explants using polypyrrole/BDNF-coated electrodes.Pre-operative intravenous dexamethasone prevents auditory threshold shift in a guinea pig model of cochlear implantation.Conducting polymers, dual neurotrophins and pulsed electrical stimulation--dramatic effects on neurite outgrowth.The effect of polypyrrole with incorporated neurotrophin-3 on the promotion of neurite outgrowth from auditory neurons.Gel-Mediated Electrospray Assembly of Silica Supraparticles for Sustained Drug DeliveryEffects of Round Window Dexamethasone on Residual Hearing in a Guinea Pig Model of Cochlear ImplantationNovel drug delivery systems for inner ear protection and regeneration after hearing lossEffect of the dopant anion in polypyrrole on nerve growth and release of a neurotrophic proteinPharmacokinetics and tissue distribution of neurotrophin 3 after intracochlear deliveryNew molecular therapies for the treatment of hearing lossCombined optogenetic and electrical stimulation of auditory neurons increases effective stimulation frequency-an in vitro studyEngineering Biocoatings To Prolong Drug Release from Supraparticles
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P50
description
researcher, ORCID id # 0000-0002-2412-8354
@en
wetenschapper
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name
R Richardson
@ast
R Richardson
@en
R Richardson
@nl
type
label
R Richardson
@ast
R Richardson
@en
R Richardson
@nl
prefLabel
R Richardson
@ast
R Richardson
@en
R Richardson
@nl
P106
P31
P496
0000-0002-2412-8354