about
Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors.An internal thioester in a pathogen surface protein mediates covalent host bindingDevelopment of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors.The trypanosome alternative oxidase: a potential drug target?Simplifying nature: Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins.Magnetic retraction of bowel by intraluminal injectable cyanoacrylate-based magnetic glue.Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues.Stereocontrolled Total Synthesis of (-)-Aurisides A and BDiscodermolide interferes with the binding of tau protein to microtubules.A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel.Kinetics and Structure of a Cold-Adapted Hetero-Octameric ATP Phosphoribosyltransferase.Total synthesis, stereochemical assignment, and biological activity of chamuvarinin and structural analogues.Total synthesis of (-)-reidispongiolide A, an actin-targeting macrolide isolated from the marine sponge Reidispongia coerulea.Design and Synthesis of Broad Spectrum Trypanosomatid Selective Inhibitors.Intraluminal magnetisation of bowel by ferromagnetic particles for retraction and manipulation by magnetic probes.Mucoadhesive polymer films for tissue retraction in laparoscopic surgery: Ex-vivo study on their mechanical properties.Total Synthesis of the Antimicrotubule Agent (+)-Discodermolide Using Boron-Mediated Aldol Reactions of Chiral Ketones1,6-asymmetric induction in boron-mediated aldol reactions: application to a practical total synthesis of (+)-discodermolideTotal synthesis and stereochemical reassignment of (+)-dolastatin 19The chemical synthesis of discodermolideSynthesis of the originally proposed structure of palmerolide CStructure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP SynthaseApproaches to CNS Drug Delivery with a Focus on Transporter-Mediated Transcytosis
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P50
description
onderzoeker
@nl
researcher, ORCID id # 0000-0001-9921-4399
@en
name
Gordon J Florence
@ast
Gordon J Florence
@en
Gordon J Florence
@es
Gordon J Florence
@nl
type
label
Gordon J Florence
@ast
Gordon J Florence
@en
Gordon J Florence
@es
Gordon J Florence
@nl
prefLabel
Gordon J Florence
@ast
Gordon J Florence
@en
Gordon J Florence
@es
Gordon J Florence
@nl
P106
P1153
7003626505
P31
P496
0000-0001-9921-4399