Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors - Wikidata - wikimedia - TriplyDB

Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors

Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors

http://www.wikidata.org/entity/Q58426250

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Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular Effects Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer.Modulation of inflammation by autophagy: Consequences for human disease Oncogenic mutations of PIK3CA in human cancers Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo.Notch signaling in glioblastoma: a developmental drug target?The PI3K-Akt-mTOR pathway in initiation and progression of thyroid tumors.Potent inhibition of thyroid cancer cells by the MEK inhibitor PD0325901 and its potentiation by suppression of the PI3K and NF-kappaB pathways Highly frequent promoter methylation and PIK3CA amplification in non-small cell lung cancer (NSCLC).NF-kappaB/STAT3/PI3K signaling crosstalk in iMyc E mu B lymphoma.Autophagy: A potential target for thyroid cancer therapy (Review)Relative quantification of PIK3CA gene expression level in fine-needle aspiration biopsy thyroid specimens collected from patients with papillary thyroid carcinoma and non-toxic goitre by real-time RT-PCR.Signaling networks associated with AKT activation in non-small cell lung cancer (NSCLC): new insights on the role of phosphatydil-inositol-3 kinase.Molecular pathogenesis and mechanisms of thyroid cancer Mutational analyses of the BRAF, KRAS, and PIK3CA genes in oral squamous cell carcinoma.IQGAP1 plays an important role in the invasiveness of thyroid cancer Utility of a PI3K/mTOR inhibitor (NVP-BEZ235) for thyroid cancer therapy.Single nucleotide polymorphism rs17849071 G/T in the PIK3CA gene is inversely associated with follicular thyroid cancer and PIK3CA amplification.Recent advances in molecular diagnosis of thyroid cancer.Follicular adenoma and carcinoma of the thyroid gland.Mechanisms of Trastuzumab resistance in ErbB2-driven breast cancer and newer opportunities to overcome therapy resistance.Employing genetic markers to improve diagnosis of thyroid tumor fine needle biopsy.Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma.Frequent gene amplification predicts poor prognosis in gastric cancer.Mutation of the PIK3CA oncogene in human cancers The chromosome 3q26 OncCassette: A multigenic driver of human cancer.Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS.Dysregulation of the phosphatidylinositol 3-kinase pathway in thyroid neoplasia.FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma Recent advances in molecular biology of thyroid cancer and their clinical implications.Disulfiram treatment facilitates phosphoinositide 3-kinase inhibition in human breast cancer cells in vitro and in vivo.Genetic alterations in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer cells to therapeutic targeting of Akt and mammalian target of rapamycin.AIB1 Genomic Amplification Predicts Poor Clinical Outcomes in Female Glioma Patients Molecular markers of aggressiveness of thyroid cancer.Genetic alterations in the phosphatidylinositol-3 kinase/Akt pathway in thyroid cancer.New phosphatidylinositol 3-kinase inhibitors for cancer.The mTOR protein as a target in thyroid cancer.Cytologic and molecular diagnosis of thyroid cancers: is it time for routine reflex testing?Targeting the PI3K pathway for cancer therapy.Imaging, genetic testing, and biomarker assessment of follicular cell-derived thyroid cancer.

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Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors

http://www.wikidata.org/entity/Q58426250

description

im August 2005 veröffentlichter wissenschaftlicher Artikel

@de

scientific article published on 31 May 2005

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в серпні 2005

@uk

name

Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors

@en

Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors

@nl

type

label

Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors

@en

Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors

@nl

prefLabel

Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors

@en

Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors

@nl

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The Journal of Clinical Endocrinology and Metabolism

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Uncommon mutation, but common amplifications, of the PIK3CA gene in thyroid tumors

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Barry Trink

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David Sidransky

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Elizabeth Mambo

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Guojun Wu

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Mingzhao Xing

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Paul W Ladenson

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Shuiying Hu

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Xin Huang

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Zhongmin Guo

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4688-4693

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scholarly article

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10.1210/JC.2004-2281

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8

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90

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Susanne M Gollin

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2005-05-31T00:00:00Z

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15928251

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