Nociceptin/orphanin FQ receptor ligands and translational challenges: focus on cebranopadol as an innovative analgesic

about

Nociceptin/orphanin FQ receptor ligands and translational challenges: focus on cebranopadol as an innovative analgesic

Item

http://www.wikidata.org/entity/Q58545262

description

im November 2018 veröffentlichter wissenschaftlicher Artikel

@de

scientific article published on 22 August 2018

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в листопаді 2018

@uk

name

Nociceptin/orphanin FQ recepto ...... dol as an innovative analgesic

@en

Nociceptin/orphanin FQ recepto ...... dol as an innovative analgesic

@nl

type

Item

label

Nociceptin/orphanin FQ recepto ...... dol as an innovative analgesic

@en

Nociceptin/orphanin FQ recepto ...... dol as an innovative analgesic

@nl

prefLabel

Nociceptin/orphanin FQ recepto ...... dol as an innovative analgesic

@en

Nociceptin/orphanin FQ recepto ...... dol as an innovative analgesic

@nl

P1476

Nociceptin/orphanin FQ recepto ...... dol as an innovative analgesic

@en

P2093

G Calo

http://www.w3.org/2001/XMLSchema#string

P2860

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

Pharmacological characterization of the novel nociceptin/orphanin FQ receptor ligand, ZP120: in vitro and in vivo studies in mice

Functional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonists

Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic

Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one (J-113397)

Modification of nociception and morphine tolerance by the selective opiate receptor-like orphan receptor antagonist (-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol (SB-612111)

Nociceptin receptor antagonists display antidepressant-like properties in the mouse forced swimming test

Orphanin FQ acts as an anxiolytic to attenuate behavioral responses to stress

Pharmacological characterization of the newly synthesized nociceptin/orphanin FQ-receptor agonist 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole as an anxiolytic agent

The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential

P304

1105-1114

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.BJA.2018.06.024

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

121

http://www.w3.org/2001/XMLSchema#string

P50

David G Lambert

P577

2018-08-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

30336855

http://www.w3.org/2001/XMLSchema#string

P921

nociceptin

P932

6208290

http://www.w3.org/2001/XMLSchema#string