Synthesis of 3-aminocoumarin--benzylpyridinium conjugates with nanomolar inhibitory activity against acetylcholinesterase

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Synthesis of 3-aminocoumarin--benzylpyridinium conjugates with nanomolar inhibitory activity against acetylcholinesterase

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im Januar 2018 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 02 October 2018

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wetenschappelijk artikel

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наукова стаття, опублікована у 2018

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Synthesis of 3-aminocoumarin-- ...... y against acetylcholinesterase

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Synthesis of 3-aminocoumarin-- ...... y against acetylcholinesterase

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Synthesis of 3-aminocoumarin-- ...... y against acetylcholinesterase

@en

Synthesis of 3-aminocoumarin-- ...... y against acetylcholinesterase

@nl

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Synthesis of 3-aminocoumarin-- ...... y against acetylcholinesterase

@en

Synthesis of 3-aminocoumarin-- ...... y against acetylcholinesterase

@nl

P1476

Synthesis of 3-aminocoumarin-N ...... y against acetylcholinesterase

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P2093

Cherdchai Laongthipparos

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Nisachon Khunnawutmanotham

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Nitirat Chimnoi

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Patchreenart Saparpakorn

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P2860

Mutagenesis of human acetylcholinesterase. Identification of residues involved in catalytic activity and in polypeptide folding

Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket

A new and rapid colorimetric determination of acetylcholinesterase activity

Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site.

Structures of human acetylcholinesterase in complex with pharmacologically important ligands

Development and validation of a genetic algorithm for flexible docking

Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein

The peripheral anionic site of acetylcholinesterase: structure, functions and potential role in rational drug design.

Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils.

Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease.

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2545-2552

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scholarly article

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10.3762/BJOC.14.231

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English

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Supanna Techasakul

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2018-10-02T00:00:00Z

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30410615

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6204823

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