Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation
about
IL-7 in allogeneic transplant: clinical promise and potential pitfallsProgressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection"Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responsesDevelopment of a quantitative bead capture assay for soluble IL-7 receptor alpha in human plasma.Altered T cell memory and effector cell development in chronic lymphatic filarial infection that is independent of persistent parasite antigen.Exhausted CD8 T cells downregulate the IL-18 receptor and become unresponsive to inflammatory cytokines and bacterial co-infections.Impaired selectin-dependent leukocyte recruitment induces T-cell exhaustion and prevents chronic allograft vasculopathy and rejection.Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes.Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infectionExpression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection.T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection.Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection.Tumor necrosis factor-alpha blockage therapy impairs hepatitis B viral clearance and enhances T-cell exhaustion in a mouse modelPegylated interferon α enhances recovery of memory T cells in e antigen positive chronic hepatitis B patientsT cells from patients with Candida sepsis display a suppressive immunophenotypeReactive oxygen species delay control of lymphocytic choriomeningitis virusExpression of γ-chain cytokine receptors on CD8+ T cells in HIV infection with a focus on IL-7Rα (CD127).Differences in systemic adaptive immunity contribute to the 'frequent exacerbator' COPD phenotype.Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection.Persistent hepatitis C virus (HCV) infection impairs HCV-specific cytotoxic T cell reactivity through Mcl-1/Bim imbalance due to CD127 down-regulation.Immunophenotypic shift of memory CD8 T cells identifies the changes of immune status in the patients after liver transplantation.The immunocytokine L19-IL2: An interplay between radiotherapy and long-lasting systemic anti-tumour immune responses.
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P2860
Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation
description
im Februar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 01 March 2005
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в лютому 2005
@uk
name
Inverse correlation between IL ...... persistent antigen stimulation
@en
Inverse correlation between IL ...... persistent antigen stimulation
@nl
type
label
Inverse correlation between IL ...... persistent antigen stimulation
@en
Inverse correlation between IL ...... persistent antigen stimulation
@nl
prefLabel
Inverse correlation between IL ...... persistent antigen stimulation
@en
Inverse correlation between IL ...... persistent antigen stimulation
@nl
P2093
P2860
P50
P356
P1476
Inverse correlation between IL ...... persistent antigen stimulation
@en
P2093
Hans Hengartner
Karl S Lang
Max Löhning
Mike Recher
Rolf M Zinkernagel
Tobias Junt
P2860
P304
P356
10.1002/EJI.200425828
P407
P577
2005-03-01T00:00:00Z