about
Innate nuclear sensor IFI16 translocates into the cytoplasm during the early stage of in vitro human cytomegalovirus infection and is entrapped in the egressing virions during the late stage.Nuclear DNA sensor IFI16 as circulating protein in autoimmune diseases is a signal of damage that impairs endothelial cells through high-affinity membrane binding.The proapoptotic activity of the Interferon-inducible gene IFI16 provides new insights into its etiopathogenetic role in autoimmunity.Anti-inflammatory and vascularprotective properties of 8-prenylapigenin.Role of the interferon-inducible IFI16 gene in the induction of ICAM-1 by TNF-alpha.A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells.The epithelial-mesenchymal transition induced by keratinocyte growth conditions is overcome by E6 and E7 from HPV16, but not HPV8 and HPV38: characterization of global transcription profiles.Up-regulation of the interferon-inducible IFI16 gene by oxidative stress triggers p53 transcriptional activity in endothelial cells.The Human Cytomegalovirus Tegument Protein pp65 (pUL83) Dampens Type I Interferon Production by Inactivating the DNA Sensor cGAS without Affecting STING.The Viral Tegument Protein pp65 Impairs Transcriptional Upregulation of IL-1β by Human Cytomegalovirus through Inhibition of NF-kB ActivityTumor-Derived Endothelial Cells Evade Apoptotic Activity of the Interferon-Inducible IFI16 Gene
P50
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P50
description
researcher ORCID ID = 0000-0001-6389-5129
@en
wetenschapper
@nl
name
Francesca Gugliesi
@ast
Francesca Gugliesi
@en
Francesca Gugliesi
@es
Francesca Gugliesi
@nl
type
label
Francesca Gugliesi
@ast
Francesca Gugliesi
@en
Francesca Gugliesi
@es
Francesca Gugliesi
@nl
prefLabel
Francesca Gugliesi
@ast
Francesca Gugliesi
@en
Francesca Gugliesi
@es
Francesca Gugliesi
@nl
P106
P1153
8635984500
P31
P496
0000-0001-6389-5129